CAS Number67604-48-2
SynonymsNaringenin; (+)-(2R)-naringenin; (R)-naringenin; 4',5,7-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; (+)-Naringenin; MFCD00006844; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; Naringenine; EINECS 266-769-1
Molecular FormulaC15H12O5
Molecular Weight272.25
Purity98.00%
Density1.485g/cm3
Boiling Point577.5ºC at 760mmHg
Melting Point247-250 °C(lit.)
AppearanceSolid;White to Light yellow to Light orange powder to crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 67604-48-2 |
| Catalog No. | 2A-9094075 |
| Chinese Name | 柚皮素 |
| Synonyms | Naringenin; (+)-(2R)-naringenin; (R)-naringenin; 4',5,7-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; (+)-Naringenin; MFCD00006844; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; Naringenine; EINECS 266-769-1 |
| Molecular Formula | C15H12O5 |
| Molecular Weight | 272.25 |
| Purity | 98.00 |
| Density | 1.485g/cm3 |
| Boiling Point | 577.5ºC at 760mmHg |
| Melting Point | 247-250 °C(lit.) |
| Appearance | Solid;White to Light yellow to Light orange powder to crystal |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | (±)-Naringenin is a natural flavonoid. (±)-Naringenin exerts vasodilatory effects on endothelial-denuded blood vessels by activating BKCa channels in myocytes. |
| PubChem ID | 329757794 |
| SMILES | O=C1CC(c2ccc(O)cc2)Oc2cc(O)cc(O)c21 |
| InChI | InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2 |
| InChI Key | FTVWIRXFELQLPI-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | (±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Saponara S, et al. (±)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells. Br J Pharmacol. 2006 Dec;149(8):1013-21. Chemical & Physical Properties Density 1.485g/cm3 Boiling Point 577.5ºC at 760mmHg Melting Point 247-250 °C(lit.) Molecular Formula C15H12O5 Molecular Weight 272.25300 Exact Mass 272.06800 PSA 83.83000 LogP 2.13750 InChIKey FTVWIRXFELQLPI-UHFFFAOYSA-N SMILES O=C1CC(c2ccc(O)cc2)Oc2cc(O)cc(O)c21 Storage condition 0-6°C |
| Use of | (±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1]. Properties Articles87 Name 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one Synonym More Synonyms (±)-Naringenin Biological Activity Description (±)-Naringenin is a naturally-occurring flavonoid. (±)-Naringenin displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Saponara S, et al. (±)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells. Br J Pharmacol. 2006 Dec;149(8):1013-21. Chemical & Physical Properties Molecular Formula C15H12O5 Exact Mass 272.06800 PSA 83.83000 LogP 2.13750 InChIKey FTVWIRXFELQLPI-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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