LOXO-101 (sulfate)

Name: LOXO-101 (sulfate)
Brand: 2A Biotech
SKU: 2A-9093876

CAS Number1223405-08-0

SynonymsUNII:RDF76R62ID; Larotrectinib sulfate; LOXO-101 sulfate; LOXO-101 (sulfate)

Molecular FormulaC21H24F2N6O6S

Molecular Weight526.514

Appearanceyellow powder

Cat. No.: 2A-9093876 Purity:

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Quality Control of [ 1223405-08-0 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1223405-08-0
Catalog No.	2A-9093876
Chinese Name	硫酸拉罗替尼
Synonyms	UNII:RDF76R62ID; Larotrectinib sulfate; LOXO-101 sulfate; LOXO-101 (sulfate)
Molecular Formula	C21H24F2N6O6S
Molecular Weight	526.514
Appearance	yellow powder
Storage Condition	2-8℃
Application	Larotrectinib (LOXO-101) sulfate is an ATP-competitive, orally selective inhibitor with nanomolar 50% inhibitory concentrations of three subtypes of tropomyosin-related kinase (TRK) family receptors (
PubChem ID	224521470
SMILES	O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12)N1CCC(O)C1.O=S(=O)(O)O
InChI	InChI=1S/C21H22F2N6O2.H2O4S/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27;1-5(2,3)4/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12H2,(H,25,31);(H2,1,2,3,4)/t14-,18+;/m0./s1
InChI Key	PXHANKVTFWSDSG-QLOBERJESA-N
Transport Info	Product Name: Larotinib Sulfate

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