CAS Number62989-33-7
SynonymsSapropterin; (6R,1'R,2'S)-6-(1',2'-dihydroxypropyl)-5,6,7,8-tetrahydrobiopterin; 6b-5,6,7,8-Tetrahydro-L-biopterin; Dapropterin; (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone; (6R)-5,6,7,8-tetrahydro-L-biopterin; (6R)-Tetrahydrobiopterin; 6R-tetahydrobiopterin; 6R-Tetrahydro-L-biopterin; R-THBP6R-BH4; (6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin; sapropterina; sapropterinum; (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one; R-THBP; (6R)-5,6,7,8-Tetrahydrobiopterin; (6R)-L-erythro-Tetrahydrobiopterin; [6R-[6R*(1R*,2S*)]]-2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone
Molecular FormulaC9H15N5O3
Molecular Weight314.17
Purity98.00%
Density1.9±0.1 g/cm3
Boiling Point506.6±60.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62989-33-7 |
| Catalog No. | 2A-9093866 |
| Chinese Name | 沙丙蝶呤 |
| Synonyms | Sapropterin; (6R,1'R,2'S)-6-(1',2'-dihydroxypropyl)-5,6,7,8-tetrahydrobiopterin; 6b-5,6,7,8-Tetrahydro-L-biopterin; Dapropterin; (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone; (6R)-5,6,7,8-tetrahydro-L-biopterin; (6R)-Tetrahydrobiopterin; 6R-tetahydrobiopterin; 6R-Tetrahydro-L-biopterin; R-THBP6R-BH4; (6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin; sapropterina; sapropterinum; (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one; R-THBP; (6R)-5,6,7,8-Tetrahydrobiopterin; (6R)-L-erythro-Tetrahydrobiopterin; [6R-[6R*(1R*,2S*)]]-2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone |
| Molecular Formula | C9H15N5O3 |
| Molecular Weight | 314.17 |
| Purity | 98.00 |
| Density | 1.9±0.1 g/cm3 |
| Boiling Point | 506.6±60.0 °C at 760 mmHg |
| Storage Condition | −20°C |
| Application | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor that can effectively reduce blood phenylalanine concentration. Sapropterin can be used in the research of phenylketo |
| HTC | 2933990090 |
| PubChem ID | 3570 |
| MDL Number | C9H17Cl2N5O3 |
| SMILES | CC(O)C(O)C1CNc2nc(N)[nH]c(=O)c2N1 |
| InChI | InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1 |
| InChI Key | FNKQXYHWGSIFBK-RPDRRWSUSA-N |
| MSDS | msds/93866_1_62989_33_7.pdf |
| Use of | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1]. Properties Name (6r,s)-5,6,7,8-tetrahydro-l-biopterin Synonym More Synonyms Sapropterin Biological Activity Description Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Chemical & Physical Properties Molecular Formula C9H15N5O3 Exact Mass 241.117493 PSA 136.29000 LogP -4.22 Index of Refraction 1.822 InChIKey FNKQXYHWGSIFBK-RPDRRWSUSA-N Safety Information Hazard Codes Xn Risk Phrases R22 WGK Germany 3 RTECS UO3516500 HS Code 2933990090 Synthetic Route Total: 1 Page 6-Biopterin CAS#:22150-76-1 Sapropterin CAS#:62989-33-7 (6S)-Tetrahydro... CAS#:62961-57-3 Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Heterocycles, 1985 , vol. 23, # 12 p. 3115 - 3120 (6R)-2-amino-6-... CAS#:79647-29-3 7,8-Dihydro-L-b... CAS#:6779-87-9 Sapropterin CAS#:62989-33-7 6-Biopterin CAS#:22150-76-1 Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Tetrahedron Letters, 1986 , vol. 27, # 5 p. 585 - 588 Precursor & DownStream Precursor 2 CAS#:22150-76-1 6-Biopterin CAS#:79647-29-3 (6R)-2-amino-6-... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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