
CAS Number53-84-9
Synonymsb-Diphosphopyridine Nucleotide; DPN; beta-Diphosphopyrid; MFCD00036253; Coenzyme I Hydrate,oxidized form; Diphosphopyridine nucleotide; Cozymase Hydrate,oxidized form; β-Nicotinamide adenine dinucleotide; EINECS 200-184-4; β-Diphosphopyridine Nucleotide Hydrate,oxidized form; β-NAD Hydrate,oxidized form; Adenine-D-ribose-phosphate-phosphate-D-ribose-nicotinamide; b-Nicotinamide Adenine Dinucleotide; β-DPN Hydrate,oxidized form; Codehydrogenase; β-Nicotinamide Adenine Dinucleotide Hydrate,oxidized form; ARPPRN; b-NAD; Cozymase; beta-Diphosphopyridine nucleotide; β-NAD; β-Nicotinamide adenine dinucleotide hydrate; NAD; β-DPN; NAD+
Molecular FormulaC21H27N7O14P2
Molecular Weight663.43 (anhydrous basis)
Purity≥96.5 (HPLC)%
Melting Point140 - 142ºC
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53-84-9 |
| Catalog No. | 2A-9009378 |
| Chinese Name | 辅酶I |
| Synonyms | b-Diphosphopyridine Nucleotide; DPN; beta-Diphosphopyrid; MFCD00036253; Coenzyme I Hydrate,oxidized form; Diphosphopyridine nucleotide; Cozymase Hydrate,oxidized form; β-Nicotinamide adenine dinucleotide; EINECS 200-184-4; β-Diphosphopyridine Nucleotide Hydrate,oxidized form; β-NAD Hydrate,oxidized form; Adenine-D-ribose-phosphate-phosphate-D-ribose-nicotinamide; b-Nicotinamide Adenine Dinucleotide; β-DPN Hydrate,oxidized form; Codehydrogenase; β-Nicotinamide Adenine Dinucleotide Hydrate,oxidized form; ARPPRN; b-NAD; Cozymase; beta-Diphosphopyridine nucleotide; β-NAD; β-Nicotinamide adenine dinucleotide hydrate; NAD; β-DPN; NAD+ |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.43 (anhydrous basis) |
| Purity | ≥96.5 (HPLC) |
| Melting Point | 140 - 142ºC |
| Appearance | powder |
| Storage Condition | This product should be sealed and stored dry at 4° |
| Application | NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions. NAD+ is the oxidized form of NADH. |
| HTC | 29349990 |
| PubChem ID | 24897803 |
| MDL Number | MFCD00036253 |
| SMILES | NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O |
| InChI | 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 |
| InChI Key | BAWFJGJZGIEFAR-NNYOXOHSSA-N |
| NACRES Code | NA.55 |
| eCl@ss | 39200202 |
| UNSPSC | 41106305 |
| Hazard Symbols | Transport |
| MSDS | msds/9378_1_53_84_9.pdf |
| Bioactivity | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Related Catalog Research Areas >> Metabolic Disease Natural Products >> Saccharides and Glycosides Target Human Endogenous Metabolite In Vitro NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH[1]. NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) [2]. In Vivo Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia[3]. References [1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12. Chemical & Physical Properties Melting Point 140 - 142ºC Molecular Formula C21H27N7O14P2 Molecular Weight 663.425 Exact Mass 663.109131 PSA 340.71000 LogP -5.72 InChIKey BAWFJGJZGIEFAR-NNYOXOHSSA-O SMILES NC(=O)c1ccc[n+](C2OC(COP(=O)(O)OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)C(O)C3O)C(O)C2O)c1 |
| Use of | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Properties Articles286 Name NAD zwitterion Synonym More Synonyms NAD+ Biological Activity Description NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Related Catalog Research Areas >> Metabolic Disease Natural Products >> Saccharides and Glycosides Human Endogenous Metabolite In Vitro NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ is the oxidized form of NADH[1]. NAD+ is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) [2]. In Vivo Oral NAD+ supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia[3]. References [1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70. [2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92. [3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12. Chemical & Physical Properties Molecular Formula C21H27N7O14P2 Exact Mass 663.109131 PSA 340.71000 LogP -5.72 InChIKey BAWFJGJZGIEFAR-NNYOXOHSSA-O |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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