| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1421373-65-0 |
| Catalog No. | 2A-9092748 |
| Chinese Name | 奥斯替尼 |
| Synonyms | Osimertinib; Mereletinib; AZD-9291 |
| Molecular Formula | C28H33O2N7 |
| Molecular Weight | 499.62 |
| Density | 1.2±0.1 g/cm3 |
| Storage Condition | room temperature, dry |
| Application | Osimertinib (AZD-9291) is an irreversible and mutant-selective EGFR inhibitor with IC50s of 12 and 1 nM for EGFRL858R and EGFRL858R/T790M, respectively. |
| HTC | 29339900 |
| PubChem ID | 163477648 |
| MDL Number | MFCD27988062 |
| SMILES | C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C |
| InChI | InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32) |
| InChI Key | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| MSDS | msds/92748_1_1421373_65_0.pdf |
| Transport Info | Product name: Osimertinib base |
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