| Chemical & Physical Properties | |
|---|---|
| CAS Number | 134523-00-5 |
| Catalog No. | 2A-9009259 |
| Chinese Name | 阿伐他汀 |
| Synonyms | Atorvastatin; MFCD03613598 |
| Molecular Formula | C33H35FN2O5 |
| Molecular Weight | 558.64 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 722.2±60.0 °C at 760 mmHg |
| Melting Point | 176-178°C |
| Appearance | solid |
| Storage Condition | Room Temperature |
| Packaging | III |
| Application | Atorvastatin is an HMG-CoA reductase inhibitor that inhibits cholesterol production. |
| HTC | 2942000000 |
| SMILES | CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC(O)CC(O)CC(=O)O |
| InChI | 1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1 |
| InChI Key | XUKUURHRXDUEBC-KAYWLYCHSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 8 |
| MSDS | msds/9259_1_134523_00_5.pdf |
| Use of | Properties Name atorvastatin Synonym More Synonyms Atorvastatin Biological Activity Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR) Research Areas >> Metabolic Disease References [1]. Nawrocki, J.W., et al., Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb Vasc Biol, 1995. 15(5): p. 678-82. [2]. Colhoun, H.M., et al., Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet, 2004. 364(9435): p. 685-96. Chemical & Physical Properties Molecular Formula C33H35FN2O5 PSA 229.24000 Index of Refraction 1.603 InChIKey XUKUURHRXDUEBC-KAYWLYCHSA-N Safety Information Hazard Codes Xn WGK Germany 2 Packaging Group III Hazard Class 8 HS Code 2942000000 Synthetic Route Atorvastatin ca... 134523-03-8 Atorvastatin 134523-00-5 Atorvastatin te... 134395-00-9 Atorvastatin 134523-00-5 Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270 Atorvastatin Ac... 125971-95-1 Atorvastatin 134523-00-5 Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 3 p. 261 - 270 Precursor & DownStream Precursor 8 CAS#:134395-00-9 Atorvastatin te... CAS#:125971-95-1 Atorvastatin Ac... CAS#:1049684-97-0 ((4R,6R)-6-(2-[... CAS#:134523-01-6 Atorvastatin Sodium DownStream 3 CAS#:125995-03-1 Atorvastatin lactone CAS#:345891-62-5 Atorvastatin me... CAS#:134523-01-6 Atorvastatin Sodium |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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