CAS Number1143-38-0
Synonyms1,8,9-Trihydroxyanthracene; Anthralin; Dithranol; Cigthranol; MFCD00053409; Batridol; 1,8-Dihydroxy-9(10H)-anthracenone; 1,8,9-Anthracenetriol (1,8-Dihydroxy-9(10H)-anthracenone; 1,8-dihydroxy-9-anthrone; 1,8-Dihydroxyanthracen-9(10H)-one; EINECS 214-538-0; MFCD00001250; 1,8-dihydroxy-10H-anthracen-9-one; 1,8-dihydro-9,10H-anthracenone; Chrysodermol; Anthrone,1,8-dihydroxy; 1,8-Dihydroxyanthrone
Molecular FormulaC14H10O3
Molecular Weight226.23
Purity≥90 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point464.1±45.0 °C at 760 mmHg
Melting Point178-181 °C (lit.)
Appearancesolid
EINECS214-538-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1143-38-0 |
| Catalog No. | 2A-9009211 |
| Chinese Name | 1,8,9-三羟基蒽 |
| Synonyms | 1,8,9-Trihydroxyanthracene; Anthralin; Dithranol; Cigthranol; MFCD00053409; Batridol; 1,8-Dihydroxy-9(10H)-anthracenone; 1,8,9-Anthracenetriol (1,8-Dihydroxy-9(10H)-anthracenone; 1,8-dihydroxy-9-anthrone; 1,8-Dihydroxyanthracen-9(10H)-one; EINECS 214-538-0; MFCD00001250; 1,8-dihydroxy-10H-anthracen-9-one; 1,8-dihydro-9,10H-anthracenone; Chrysodermol; Anthrone,1,8-dihydroxy; 1,8-Dihydroxyanthrone |
| Molecular Formula | C14H10O3 |
| Molecular Weight | 226.23 |
| Purity | ≥90 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 464.1±45.0 °C at 760 mmHg |
| Melting Point | 178-181 °C (lit.) |
| Appearance | solid |
| Water Solubility | Water solubility: insoluble; soluble in: dimethylf |
| Storage Condition | Sealed, stored at 2ºC -8ºC |
| Application | Dithranol is highly effective in treating psoriasis. |
| EINECS | 214-538-0 |
| HTC | 2914400090 |
| PubChem ID | 24893712 |
| MDL Number | MFCD00053409 |
| SMILES | Oc1cccc2Cc3cccc(O)c3C(=O)c12 |
| InChI | 1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2 |
| InChI Key | NUZWLKWWNNJHPT-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2054360 |
| NACRES Code | NA.25 |
| UNSPSC | 12352201 |
| Hazard Symbols | Transport |
| MSDS | msds/9211_1_1143_38_0.pdf |
| Bioactivity | Dithranol is highly effective in the treatment of psoriasis.Target: OthersDithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. http://en.wikipedia.org/wiki/Dithranol Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 464.1±45.0 °C at 760 mmHg Melting Point 178-181 °C(lit.) Molecular Formula C14H10O3 Molecular Weight 226.227 Flash Point 248.6±25.2 °C Exact Mass 226.062988 PSA 57.53000 LogP 4.16 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.710 InChIKey NUZWLKWWNNJHPT-UHFFFAOYSA-N SMILES O=C1c2c(O)cccc2Cc2cccc(O)c21 Storage condition 2-8°C Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Use of | Dithranol is highly effective in the treatment of psoriasis.Target: OthersDithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis. Properties Articles36 Name anthralin Synonym More Synonyms Dithranol Biological Activity Description Dithranol is highly effective in the treatment of psoriasis.Target: OthersDithranol accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals. This impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques. In addition Dithranol may act by reducing the elevated levels of cGMP that occurs in psoriasis. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. http://en.wikipedia.org/wiki/Dithranol Chemical & Physical Properties Molecular Formula C14H10O3 Exact Mass 226.062988 PSA 57.53000 Index of Refraction 1.710 InChIKey NUZWLKWWNNJHPT-UHFFFAOYSA-N Stability Stable. Combustible. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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