CAS Number51037-30-0
Synonyms5-methyl-2-pyrazinoic-4-oxide; 2-Pyrazinecarboxylic acid, 5-methyl-, 4-oxide; 2-Carboxy-5-methylpyrazine 4-oxide,5-Methylpyrazinecarboxylic acid 4-oxide; 5-Carboxy-2-methylpyrazine 1-oxide; 5-methyl-4-oxy-pyrazine-2-carboxylic acid; 5-methylpyrazine-2-carboxylic acid 4-oxide; 2-carboxy-5-methylpyrazine 4-oxide; Acipimox; K-9321; Olbetam; 5-Methylpyrazinecarboxylic acid 4-oxide; 5-Methyl-2-pyrazinecarboxylic acid 4-oxide; 2-methyl-5-pyrazinecarboxylic acid 1-oxide; Olbemox; EINECS 256-928-3; T6N DNJ AO B1 EVQ; MFCD00865757
Molecular FormulaC6H6O3N2
Molecular Weight154.13
Purity98%
Density1.4±0.1 g/cm3
Boiling Point539.0±45.0 °C at 760 mmHg
Melting Point177-180 °C
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51037-30-0 |
| Catalog No. | 2A-9009047 |
| Chinese Name | 阿西莫司 |
| Synonyms | 5-methyl-2-pyrazinoic-4-oxide; 2-Pyrazinecarboxylic acid, 5-methyl-, 4-oxide; 2-Carboxy-5-methylpyrazine 4-oxide,5-Methylpyrazinecarboxylic acid 4-oxide; 5-Carboxy-2-methylpyrazine 1-oxide; 5-methyl-4-oxy-pyrazine-2-carboxylic acid; 5-methylpyrazine-2-carboxylic acid 4-oxide; 2-carboxy-5-methylpyrazine 4-oxide; Acipimox; K-9321; Olbetam; 5-Methylpyrazinecarboxylic acid 4-oxide; 5-Methyl-2-pyrazinecarboxylic acid 4-oxide; 2-methyl-5-pyrazinecarboxylic acid 1-oxide; Olbemox; EINECS 256-928-3; T6N DNJ AO B1 EVQ; MFCD00865757 |
| Molecular Formula | C6H6O3N2 |
| Molecular Weight | 154.13 |
| Purity | 98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 539.0±45.0 °C at 760 mmHg |
| Melting Point | 177-180 °C |
| Storage Condition | Keep the receptacle sealed, stored in a cool, dry |
| Application | Acipimox is a niacin derivative that can lower blood lipids. |
| HTC | 2942000000 |
| MDL Number | MFCD00865757 |
| SMILES | Cc1cnc(C(=O)O)c[n+]1[O-] |
| InChI | InChI=1S/C6H6N2O3/c1-4-2-7-3-5(6(9)10)8(4)11/h2-3H,1H3,(H,9,10) |
| InChI Key | DJQOOSBJCLSSEY-UHFFFAOYSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/9047_1_51037_30_0.pdf |
| Bioactivity | Acipimox is a niacin derivative used as a hypolipidemic agent.Target: Acipimox is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. Long-term administration is associated with reduced mortality, but unwanted effects limit its clinical use. Adverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox. High doses can cause disorders of liver function, impair glucose tolerance and precipitate gout. From Wikipedia. Related Catalog Signaling Pathways >> Others >> Others Natural Products >> Alkaloid Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Acipimox Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 539.0±45.0 °C at 760 mmHg Melting Point 177-180 °C Molecular Formula C6H6N2O3 Molecular Weight 154.123 Flash Point 279.8±28.7 °C Exact Mass 154.037842 PSA 75.65000 LogP -1.38 Vapour Pressure 0.0±1.5 mmHg at 25°C Index of Refraction 1.608 InChIKey DJQOOSBJCLSSEY-UHFFFAOYSA-N SMILES Cc1cnc(C(=O)O)c[n+]1[O-] Storage condition 2-8°C |
| Use of | Properties Articles30 Name 5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid Synonym More Synonyms Acipimox Biological Activity Related Catalog Signaling Pathways >> Others >> Others Natural Products >> Alkaloid Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Acipimox Chemical & Physical Properties Molecular Formula C6H6N2O3 Exact Mass 154.037842 PSA 75.65000 LogP -1.38 Index of Refraction 1.608 InChIKey DJQOOSBJCLSSEY-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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