CAS Number64-75-5
Synonymsachromycin hydrochloride; paltet; u-5965; EINECS 200-593-8; alatet; partrex; Tetracycline (hydrochloride); tetracycline HCl; teline; MFCD00078142; sumycin; tet-cy; quatrex; qidtet; unicin
Molecular FormulaC22H25ClN2O8
Molecular Weight480.90
Purity95%
Boiling Point799.4ºC at 760 mmHg
Melting Point220-223 °C (lit.)
Appearancecrystalline powder
EINECS200-593-8
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 64-75-5 |
| Catalog No. | 2A-9009045 |
| Chinese Name | 盐酸四环素 |
| Synonyms | achromycin hydrochloride; paltet; u-5965; EINECS 200-593-8; alatet; partrex; Tetracycline (hydrochloride); tetracycline HCl; teline; MFCD00078142; sumycin; tet-cy; quatrex; qidtet; unicin |
| Molecular Formula | C22H25ClN2O8 |
| Molecular Weight | 480.90 |
| Purity | 95 |
| Boiling Point | 799.4ºC at 760 mmHg |
| Melting Point | 220-223 °C (lit.) |
| Appearance | crystalline powder |
| Water Solubility | 50 g/L |
| Storage Condition | This product should be sealed and stored in a dry |
| Application | Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a variety of infections. |
| EINECS | 200-593-8 |
| HTC | 29413000 |
| MDL Number | MFCD00078142 |
| SMILES | Cl.CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O |
| InChI | 1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1 |
| InChI Key | XMEVHPAGJVLHIG-FMZCEJRJSA-N |
| Beilstein/REAXYS | 3844873 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/9045_1_64_75_5.pdf |
| Bioactivity | Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a wide range of infections. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection In Vitro Tetracyclines are broad-spectrum agents, exhibiting activity against a wide range of gram-positive and gram-negative bacteria, atypical organisms such as chlamydiae, mycoplasmas, and rickettsiae, and protozoan parasites. Tetracyclines inhibit bacterial protein synthesis by preventing the association of aminoacyl-tRNA with the bacterial ribosome. Tetracyclines traverse the outer membrane of gram-negative enteric bacteria through the OmpF and OmpC porin channels, as positively charged cation (probably magnesium)-tetracycline coordination complexes [1]. In Vivo The tetracyclines have applications for the treatment of infections in poultry, cattle, sheep, and swine. In some cases, e.g., for therapeutic treatment of large numbers of poultry reared on commercial farms, the antibiotics are added directly to feed or water or can be administered in aerosols. Tetracyclines could be used as growth promotion or growth enhancement. Tetracyclines are used in aquaculture to control infections in salmon, catfish, and lobsters[2]. References [1]. Chopra I, et al.Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology ofbacterial resistance.Microbiol Mol Biol Rev. 2001 Jun;65(2):232-60 Chemical & Physical Properties Boiling Point 799.4ºC at 760 mmHg Melting Point 220-223 °C(lit.) Molecular Formula C22H25ClN2O8 Molecular Weight 480.896 Flash Point 437.3ºC Exact Mass 480.129944 PSA 181.62000 LogP 1.28790 Vapour Pressure 5.82E-27mmHg at 25°C Index of Refraction -253 ° (C=0.5, 0.1mol/L HCl) InChIKey YCIHPQHVWDULOY-FMZCEJRJSA-N SMILES CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4C(C)(O)C3CC12.Cl Water Solubility 50 g/L |
| Use of | Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a wide range of infections. Properties Articles104 Name Tetracycline hydrochloride Synonym More Synonyms Tetracycline hydrochloride Biological Activity Description Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a wide range of infections. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection In Vitro Tetracyclines are broad-spectrum agents, exhibiting activity against a wide range of gram-positive and gram-negative bacteria, atypical organisms such as chlamydiae, mycoplasmas, and rickettsiae, and protozoan parasites. Tetracyclines inhibit bacterial protein synthesis by preventing the association of aminoacyl-tRNA with the bacterial ribosome. Tetracyclines traverse the outer membrane of gram-negative enteric bacteria through the OmpF and OmpC porin channels, as positively charged cation (probably magnesium)-tetracycline coordination complexes [1]. In Vivo The tetracyclines have applications for the treatment of infections in poultry, cattle, sheep, and swine. In some cases, e.g., for therapeutic treatment of large numbers of poultry reared on commercial farms, the antibiotics are added directly to feed or water or can be administered in aerosols. Tetracyclines could be used as growth promotion or growth enhancement. Tetracyclines are used in aquaculture to control infections in salmon, catfish, and lobsters[2]. References [1]. Chopra I, et al.Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology ofbacterial resistance.Microbiol Mol Biol Rev. 2001 Jun;65(2):232-60 Chemical & Physical Properties Exact Mass 480.129944 PSA 181.62000 LogP 1.28790 InChIKey YCIHPQHVWDULOY-FMZCEJRJSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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