CAS Number67656-30-8
Synonyms10-Hydroxycamptothecin; hydroxycamtothecine; Camptothecin, 10-hydroxy; 9-hydroxy-20(S)-camptothecin; 10-hydroxy-Camptothecin; 9-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g] chromene-5,10-dione; (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10
Molecular FormulaC20H16N2O5
Molecular Weight364.351
Purity98.00%
Density1.6±0.1 g/cm3
Boiling Point820.7±65.0 °C at 760 mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 67656-30-8 |
| Catalog No. | 2A-9008954 |
| Chinese Name | 10-羟基喜树碱 |
| Synonyms | 10-Hydroxycamptothecin; hydroxycamtothecine; Camptothecin, 10-hydroxy; 9-hydroxy-20(S)-camptothecin; 10-hydroxy-Camptothecin; 9-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzo[g] chromene-5,10-dione; (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10 |
| Molecular Formula | C20H16N2O5 |
| Molecular Weight | 364.351 |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 820.7±65.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | 2-8°C, dry |
| Application | 9-Hydroxycamptothecin (9-Hydroxycamptothecine) is a camptothecin derivative with anti-cancer activity. For detailed information, please refer to compound 23c in the patent document WO1999001456A1. |
| HTC | 2934999090 |
| SMILES | CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(O)cccc3nc2-1 |
| InChI | InChI=1S/C20H16N2O5/c1-2-20(26)13-7-15-17-10(6-11-14(21-17)4-3-5-16(11)23)8-22(15)18(24)12(13)9-27-19(20)25/h3-7,21,26H,2,8-9H2,1H3/t20-/m0/s1 |
| InChI Key | LCZZWLIDINBPRC-FQEVSTJZSA-N |
| Use of | Properties Name 3,4-dihydro-9-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10-dione Synonym More Synonyms 9-Hydroxycamptothecin Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Dennis P. Curran, et al. Synthesis of and intermediates for camptothecins. WO1999001456A1. Chemical & Physical Properties Molecular Formula C20H16N2O5 Exact Mass 364.105927 PSA 101.65000 Index of Refraction 1.777 InChIKey LCZZWLIDINBPRC-FQEVSTJZSA-N Safety Information Hazard Codes Xn HS Code 2934999090 Synthetic Route Camptothecin N-... 86639-48-7 9-Hydroxycampto... 67656-30-8 Literature: US4473692 A1, ; 9-Aminocamptoth... 91421-43-1 9-Hydroxycampto... 67656-30-8 Campathecin Literature: Journal of Medicinal Chemistry, , vol. 36, # 18 p. 2689 - 2700 91421-42-0 9-Hydroxycampto... 67656-30-8 Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 17 p. 3865 - 3869 Precursor & DownStream Precursor 7 CAS#:86639-48-7 Camptothecin N-oxide CAS#:91421-43-1 9-Aminocamptothecin CAS#:91421-42-0 CAS#:606-31-5 2,6-Dinitrobenz... DownStream 1 CAS#:39026-92-1 9-Methoxycampto... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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