CAS Number4350-09-8
SynonymsTelesol; Oxyfan; oxitriptan; Cincofarm; Levothym; Oxitriptan 1; MFCD00064341; L-5HTP; (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid; EINECS 224-411-1; Serotonyl; L-5-HTP L-2-Amino-3-(5-hydroxyindolyl)propionic acid
Molecular FormulaC11H12N2O3
Molecular Weight220.22
Purity≥98 (TLC)%
Density1.5±0.1 g/cm3
Boiling Point520.6±50.0 °C at 760 mmHg
Melting Point270 °C (dec.)(lit.)
Appearancepowder
EINECS224-411-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4350-09-8 |
| Catalog No. | 2A-9008093 |
| Chinese Name | 5-羟基色氨酸 |
| Synonyms | Telesol; Oxyfan; oxitriptan; Cincofarm; Levothym; Oxitriptan 1; MFCD00064341; L-5HTP; (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid; EINECS 224-411-1; Serotonyl; L-5-HTP L-2-Amino-3-(5-hydroxyindolyl)propionic acid |
| Molecular Formula | C11H12N2O3 |
| Molecular Weight | 220.22 |
| Purity | ≥98 (TLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 520.6±50.0 °C at 760 mmHg |
| Melting Point | 270 °C (dec.)(lit.) |
| Appearance | powder |
| Water Solubility | Slightly soluble |
| Storage Condition | It should be sealed with argon gas and stored in a |
| Packaging | III |
| Application | L-5-Hydroxytryptophan (L-5-HTP) is a natural amino acid and dietary supplement that acts as an antidepressant, appetite suppressant, and sleep aid. It is a precursor of the neurotransmitter serotonin |
| EINECS | 224-411-1 |
| HTC | 2929909090 |
| PubChem ID | 24278131 |
| MDL Number | MFCD00064341 |
| SMILES | N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(O)=O |
| InChI | 1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1 |
| InChI Key | LDCYZAJDBXYCGN-VIFPVBQESA-N |
| NACRES Code | NA.77 |
| eCl@ss | 32160406 |
| UNSPSC | 12352209 |
| Hazard Symbols | 6.1 |
| MSDS | msds/8093_1_4350_09_8.pdf |
| Bioactivity | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Related Catalog Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Target Human Endogenous Metabolite References [1]. ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957). [2]. Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-9. [3]. Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7(6):570-6. [4]. Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225(1):41-6. [5]. Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45(11):1217-22. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 520.6±50.0 °C at 760 mmHg Melting Point 270 °C (dec.)(lit.) Molecular Formula C11H12N2O3 Molecular Weight 220.22 Flash Point 268.7±30.1 °C Exact Mass 220.084793 PSA 99.34000 LogP -0.14 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.737 InChIKey LDCYZAJDBXYCGN-VIFPVBQESA-N SMILES NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O Water Solubility Slightly soluble |
| Use of | L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Properties Name 5-hydroxy-L-tryptophan Synonym More Synonyms L-5-Hydroxytryptophan Biological Activity Description L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist[1]. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia[2][3][4][5]. Related Catalog Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Human Endogenous Metabolite References [1]. ARVID CARLSSON, et al. 3,4-Dihydroxyphenylalanine and 5-Hydroxytryptophan as Reserpine Antagonists. Nature 180, page1200 (1957). [2]. Caruso I, et al. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. 1990 May-Jun;18(3):201-9. [3]. Thal LJ, et al. Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. Ann Neurol. 1980 Jun;7(6):570-6. [4]. Boiardi A, et al. 5-OH-Tryptophane in migraine: clinical and neurophysiological considerations. J Neurol. 1981;225(1):41-6. [5]. Trouillas P, et al. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A double-blind study with quantified data processing. Arch Neurol. 1988 Nov;45(11):1217-22. Chemical & Physical Properties Molecular Formula C11H12N2O3 Exact Mass 220.084793 PSA 99.34000 LogP -0.14 Index of Refraction 1.737 InChIKey LDCYZAJDBXYCGN-VIFPVBQESA-N Water Solubility Slightly soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Oxitriptan) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Oxitriptan) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Oxitriptan) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| L-(+)-Ribose | 24259-59-4 | 2A-9008086 |
| L-2-Aminobutyric acid | 1492-24-6 | 2A-9008087 |
| L-2-Octanol | 5978-70-1 | 2A-9008089 |
| L-3,4-Dimethoxyphenylalanine | 55-59-4 | 2A-9008091 |
| L-4-trans-Hydroxyproline methyl ester hydrochloride salt | 40216-83-9 | 2A-9008092 |
| Lactone-(5-hydroxymethyl)orotic acid | 4156-75-6 | 2A-9008094 |
| L-Alaninamide hydrochloride | 33208-99-0 | 2A-9008095 |
| L-Alloisoleucine | 1509-34-8 | 2A-9008098 |
| L-alpha-Allyl-Gly | 16338-48-0 | 2A-9008099 |
| L-Aspartic acid beta-methyl ester hydrochloride | 16856-13-6 | 2A-9008106 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS