CAS Number1772-03-8
SynonymsGalactosamine; D-GalactosaMine HC1; 2-deoxy-2-amino-D-galactose hydrochloride; GALACTOSAMINE HCL; 2-aMino-2-deoxy-L-idose; D-GALN HCL; D-(+)-Galactosamine hydrochloride; Chondrosamine Hydrochloride; D-GALACTOSAMINE HCL; CHONDROSAMINE; EINECS 217-198-1; MFCD00135830; (2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride; D-CHONDROSAMINE HCL; GALACTOSAMINE HCL,D; N-Acetylgalactosamine hydrochloride
Molecular FormulaC6H14ClNO5
Molecular Weight215.63
Purity≥99 (HPLC)%
Boiling Point532.5ºC at 760 mmHg
Melting Point172-180 °C
Appearancepowder
EINECS217-198-1
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1772-03-8 |
| Catalog No. | 2A-9007531 |
| Chinese Name | D-氨基半乳糖盐酸盐 |
| Synonyms | Galactosamine; D-GalactosaMine HC1; 2-deoxy-2-amino-D-galactose hydrochloride; GALACTOSAMINE HCL; 2-aMino-2-deoxy-L-idose; D-GALN HCL; D-(+)-Galactosamine hydrochloride; Chondrosamine Hydrochloride; D-GALACTOSAMINE HCL; CHONDROSAMINE; EINECS 217-198-1; MFCD00135830; (2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride; D-CHONDROSAMINE HCL; GALACTOSAMINE HCL,D; N-Acetylgalactosamine hydrochloride |
| Molecular Formula | C6H14ClNO5 |
| Molecular Weight | 215.63 |
| Purity | ≥99 (HPLC) |
| Boiling Point | 532.5ºC at 760 mmHg |
| Melting Point | 172-180 °C |
| Appearance | powder |
| Water Solubility | SOLUBLE |
| Storage Condition | Sealed and stored at 2 ºC -8 ºC in a cool, dry pla |
| Application | D(+)-galactosamine (D-galactosamine) hydrochloride is an established experimental toxin that causes liver damage primarily through the production of free radicals and consumption of UTP nucleotides. D |
| EINECS | 217-198-1 |
| HTC | 2922399090 |
| PubChem ID | 24894912 |
| SMILES | Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO |
| InChI | 1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1 |
| InChI Key | CBOJBBMQJBVCMW-NQZVPSPJSA-N |
| Beilstein/REAXYS | 3697825 |
| NACRES Code | NA.25 |
| UNSPSC | 12352201 |
| Safety Description | S24/25 |
| MSDS | msds/7531_1_1772_03_8.pdf |
| Bioactivity | D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770. [2]. Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice. Biochem Biophys Rep. 2017;12:166-171. Published 2017 Oct 13. Chemical & Physical Properties Boiling Point 532.5ºC at 760 mmHg Melting Point 182-185 °C (dec.)(lit.) Molecular Formula C6H14ClNO5 Molecular Weight 215.63 Flash Point 275.8ºC Exact Mass 215.056046 PSA 116.17000 Vapour Pressure 5.53E-10mmHg at 25°C Index of Refraction 96 ° (C=1, H2O) InChIKey QKPLRMLTKYXDST-BMZZJELJSA-N SMILES Cl.NC1C(O)OC(CO)C(O)C1O Storage condition 2~8°C Water Solubility SOLUBLE |
| Use of | D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2]. Properties Name D(+)-Galactosamine hydrochloride Synonym More Synonyms D-(+)-Galactosamine hydrochloride Biological Activity Description D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure[1][2]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770. [2]. Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice. Biochem Biophys Rep. 2017;12:166-171. Published 2017 Oct 13. Chemical & Physical Properties Exact Mass 215.056046 PSA 116.17000 InChIKey QKPLRMLTKYXDST-BMZZJELJSA-N Water Solubility SOLUBLE |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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