CAS Number853-23-6
SynonymsEINECS 212-714-1; 3β-acetoxyandrost-5-en-17-one; Dehydroepiandrosterone acetate; MFCD00021119; Epiandrosterone Acetate; (3β)-17-Oxoandrost-5-en-3-ylacetat; DHEA-acetate, Dehydroepiandrosterone acetate; DHEA ACETATE; DEHYDRO EPIANDROSTERONE ACETATE; 3-Β-Hydroxy-Deoxyandrost-5-Ene-17-One-3-Acetate; DEHYDROANDROSTERONE ACETATE; DEHYDROEPIANDROSTERONE-3-ACETATE; DEHYDROISOANDROSTERONE ACETATE; DHEAacetate(prasterone acetate); DEHYDROISOANDROSTERONE-3-ACETATE; DEHYDROEPIANDROSTERONEACETATE(DHEAACETATE); Dehydroepiandrosteroneacetate; DEHYDRO EPIANDROSTERONE 3-ACETATE; 3-SS-HYDROXY-DEOXYANDROST-5-ENE-17-ONE-3-ACETATE; prasterone acetate; DEHYDRO EPIANDROSTERONE 3-ACETATE,OFF-WHITE SOLID; DHEAacetate; 3-(ACETYLOXY)ANDROST-5-ENE-17-ONE; DEHYDROEPIANDROSTERONE ACETATE(DHA); (3β)-17-Oxoandrost-5-en-
Molecular FormulaC21H30O3
Molecular Weight330.47
Purity98%
Density1.1±0.1 g/cm3
Boiling Point434.8±45.0 °C at 760 mmHg
Melting Point168-170ºC
AppearanceWhite to off-white powder or crystal
EINECS212-714-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 853-23-6 |
| Catalog No. | 2A-9007537 |
| Chinese Name | 醋酸去氢表雄酮 |
| Synonyms | EINECS 212-714-1; 3β-acetoxyandrost-5-en-17-one; Dehydroepiandrosterone acetate; MFCD00021119; Epiandrosterone Acetate; (3β)-17-Oxoandrost-5-en-3-ylacetat; DHEA-acetate, Dehydroepiandrosterone acetate; DHEA ACETATE; DEHYDRO EPIANDROSTERONE ACETATE; 3-Β-Hydroxy-Deoxyandrost-5-Ene-17-One-3-Acetate; DEHYDROANDROSTERONE ACETATE; DEHYDROEPIANDROSTERONE-3-ACETATE; DEHYDROISOANDROSTERONE ACETATE; DHEAacetate(prasterone acetate); DEHYDROISOANDROSTERONE-3-ACETATE; DEHYDROEPIANDROSTERONEACETATE(DHEAACETATE); Dehydroepiandrosteroneacetate; DEHYDRO EPIANDROSTERONE 3-ACETATE; 3-SS-HYDROXY-DEOXYANDROST-5-ENE-17-ONE-3-ACETATE; prasterone acetate; DEHYDRO EPIANDROSTERONE 3-ACETATE,OFF-WHITE SOLID; DHEAacetate; 3-(ACETYLOXY)ANDROST-5-ENE-17-ONE; DEHYDROEPIANDROSTERONE ACETATE(DHA); (3β)-17-Oxoandrost-5-en- |
| Molecular Formula | C21H30O3 |
| Molecular Weight | 330.47 |
| Purity | 98 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 434.8±45.0 °C at 760 mmHg |
| Melting Point | 168-170ºC |
| Appearance | White to off-white powder or crystal |
| Storage Condition | Refrigerator |
| Application | Dehydroepiandrosterone 3-acetate is a precursor of androgen/estrogen and can regulate aggressive behavior in vertebrates. |
| EINECS | 212-714-1 |
| HTC | 2937290090 |
| MDL Number | C21H30O3 |
| SMILES | CC(=O)OC1CCC2(C)C(=CCC3C4CCC(=O)C4(C)CCC32)C1 |
| InChI | InChI=1S/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/m0/s1 |
| InChI Key | NCMZQTLCXHGLOK-ZKHIMWLXSA-N |
| Hazard Symbols | Transport |
| Safety Description | S22-24/25 |
| MSDS | msds/7537_1_853_23_6.pdf |
| Bioactivity | Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression. Related Catalog Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Endocrinology In Vivo Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels[1]. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group[2]. Animal Admin The oral gavage treated with Dehydroisoandrosterone once a day for 6-week at 10.2 mg/day. SC group receives the same volume of distilled water equivalent to body weight. The Dehydroisoandrosterone supplementation in WBV+Dehydroisoandrosterone group is complete WBV training after 30 min. The recommended use of Dehydroisoandrosterone for humans is about 50 mg per one intake with a normal diet and exercise program. The mouse Dehydroisoandrosterone dose (10.2 mg/kg) used in this study is converted from a human equivalent dose on the basis of body surface area by the following formula from the US Food and Drug Administration 16: assuming a human weight of 60 kg, the human equivalent dose of 50 mg/60 kg (0.83 mg/kg)=0.83 × 12.3=a mouse dose of 10.2 mg/kg; the conversion coefficient 12.3 is used to account for differences in body surface area between a mouse and a human. References [1]. Wacker DW, et al. Dehydroepiandrosterone (DHEA) heightens aggression and increases androgen receptor and aromatase mRNA expression in the brain of a male songbird. J Neuroendocrinol. 2016 Nov 2. [2]. Chen WC, et al. Dehydroepiandrosterone Supplementation Combined with Whole-Body Vibration Training Affects Testosterone Level and Body Composition in Mice. Int J Med Sci. 2016 Sep 16;13(10):730-740. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 434.8±45.0 °C at 760 mmHg Melting Point 168-170ºC Molecular Formula C21H30O3 Molecular Weight 330.461 Flash Point 188.1±28.8 °C Exact Mass 330.219482 PSA 43.37000 LogP 4.28 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.541 InChIKey NCMZQTLCXHGLOK-ZKHIMWLXSA-N SMILES CC(=O)OC1CCC2(C)C(=CCC3C4CCC(=O)C4(C)CCC32)C1 Storage condition Refrigerator |
| Use of | Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression. Properties Name Dehydroisoandrosterone 3-acetate Synonym More Synonyms Dehydroepiandrosterone acetate Biological Activity Description Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression. Related Catalog Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Endocrinology References [1]. Wacker DW, et al. Dehydroepiandrosterone (DHEA) heightens aggression and increases androgen receptor and aromatase mRNA expression in the brain of a male songbird. J Neuroendocrinol. 2016 Nov 2. [2]. Chen WC, et al. Dehydroepiandrosterone Supplementation Combined with Whole-Body Vibration Training Affects Testosterone Level and Body Composition in Mice. Int J Med Sci. 2016 Sep 16;13(10):730-740. Chemical & Physical Properties Molecular Formula C21H30O3 Exact Mass 330.219482 PSA 43.37000 Index of Refraction 1.541 InChIKey NCMZQTLCXHGLOK-ZKHIMWLXSA-N Storage condition Refrigerator |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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