CAS Number1820-81-1
Synonyms5-Chloropyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione,5-chloro; 5-Chlorouracil; 5-chloro-2,4-dioxopyrimidine; 5-chloro-1H-pyrimidine-2,4-dione; 4-chlorouracil; 5-Chloro-2,4(1H,3H)-pyrimidinedione; EINECS 217-339-7; 5-chloro-uracil; Uracil,5-chloro; 5-Chloro-2,4-dihydroxypyrimidine; MFCD00006019; 5-Chloropyrimidine-2,4-diol
Molecular FormulaC4H3ClN2O2
Molecular Weight146.53
Purity98%
Density1.6±0.1 g/cm3
Melting Point>300 °C (lit.)
Appearancewhite crystal
EINECS217-339-7
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1820-81-1 |
| Catalog No. | 2A-9006491 |
| Chinese Name | 5-氯尿嘧啶 |
| Synonyms | 5-Chloropyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione,5-chloro; 5-Chlorouracil; 5-chloro-2,4-dioxopyrimidine; 5-chloro-1H-pyrimidine-2,4-dione; 4-chlorouracil; 5-Chloro-2,4(1H,3H)-pyrimidinedione; EINECS 217-339-7; 5-chloro-uracil; Uracil,5-chloro; 5-Chloro-2,4-dihydroxypyrimidine; MFCD00006019; 5-Chloropyrimidine-2,4-diol |
| Molecular Formula | C4H3ClN2O2 |
| Molecular Weight | 146.53 |
| Purity | 98 |
| Density | 1.6±0.1 g/cm3 |
| Melting Point | >300 °C (lit.) |
| Appearance | white crystal |
| Storage Condition | Store sealed in a cool, dry place; away from oxida |
| Application | 5-Chlorouracil (fluorouracil impurity) is a biochemical reagent that can be used as a biological material or organic compound in life science-related research. |
| EINECS | 217-339-7 |
| HTC | 29335995 |
| PubChem ID | 329749874 |
| MDL Number | MFCD00006019 |
| SMILES | ClC1=CNC(=O)NC1=O |
| InChI | 1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
| InChI Key | ZFTBZKVVGZNMJR-UHFFFAOYSA-N |
| Beilstein/REAXYS | 127173 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| Safety Description | S22;S24/25 |
| MSDS | msds/6491_1_1820_81_1.pdf |
| Bioactivity | 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Related Catalog Research Areas >> Others In Vitro 5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil. In vivo, it is converted to chlorodeoxyuridine, which is mutagenic and genotoxic. 1 Uracil is chlorinated at position 5 in a cell-free myeloperoxidase, peroxide, and chloride system where hypochlorous acid is formed 2 5-Chlorouracil has been found in inflammatory human exudates isolated from superficial infection sites in vitro and in human neutrophils stimulated with phorbol 12-myristate 13-acetate. Levels of 5-chlorouracil were increased in exudates isolated from sites of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue. 3,4 References Chemical & Physical Properties Density 1.6±0.1 g/cm3 Melting Point >300 °C(lit.) Molecular Formula C4H3ClN2O2 Molecular Weight 146.53 Flash Point 203.9ºC Exact Mass 145.988312 PSA 65.72000 LogP -0.52 Vapor Pressure 1.98E-07mmHg at 25°C Index of Refraction 1.587 InChIKey ZFTBZKVVGZNMJR-UHFFFAOYSA-N SMILES O=c1[nH]cc(Cl)c(=O)[nH]1 Storage condition Refrigerator |
| Use of | 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Catalog Research Areas >> Others In Vitro 5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil. In vivo, it is converted to chlorodeoxyuridine, which is mutagenic and genotoxic. 1 Uracil is chlorinated at position 5 in a cell-free myeloperoxidase, peroxide, and chloride system where hypochlorous acid is formed 2 5-Chlorouracil has been found in inflammatory human exudates isolated from superficial infection sites in vitro and in human neutrophils stimulated with phorbol 12-myristate 13-acetate. Levels of 5-chlorouracil were increased in exudates isolated from sites of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue. 3,4 References Chemical & Physical Properties Exact Mass 145.988312 PSA 65.72000 LogP -0.52 Index of Refraction 1.587 InChIKey ZFTBZKVVGZNMJR-UHFFFAOYSA-N SMILES O=c1[nH]cc(Cl)c(=O)[nH]1 Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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