ERLOTINIB structure, CAS 183321-74-6

ERLOTINIB

CAS Number183321-74-6

SynonymsErlotinib base; nchembio866-comp3; Erlotinib; Tarceva; UNII-J4T82NDH7E; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine; ERLOTINIB HCL; Erlotinib,OS-774; MFCD07781272; N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; OSI 744

Molecular FormulaC22H23N3O4

Molecular Weight393.44

Purity≥98 (HPLC)%

Density1.2±0.1 g/cm3

Boiling Point553.6±50.0 °C at 760 mmHg

Melting Point223 - 228ºC

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9060934 Purity: ≥98 (HPLC)%
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Quality Control of [ 183321-74-6 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number183321-74-6
Catalog No.2A-9060934
Chinese Name埃罗替尼
SynonymsErlotinib base; nchembio866-comp3; Erlotinib; Tarceva; UNII-J4T82NDH7E; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine; ERLOTINIB HCL; Erlotinib,OS-774; MFCD07781272; N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; OSI 744
Molecular FormulaC22H23N3O4
Molecular Weight393.44
Purity≥98 (HPLC)
Density1.2±0.1 g/cm3
Boiling Point553.6±50.0 °C at 760 mmHg
Melting Point223 - 228ºC
Appearancepowder
Storage Condition2~8°C
ApplicationErlotinib is a drug used to treat non-small cell lung cancer. The IC50 for inhibition of purified EGFR kinase is 2 nM.
MDL NumberMFCD02089651
SMILESN(c3cc(ccc3)C#C)c1ncnc2c1cc(c(c2)OCCOC)OCCOC
InChIInChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChI KeyAAKJLRGGTJKAMG-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/60934_1_183321_74_6.pdf
Transport InfoProduct name: Erlotinib base
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