CAS Number161796-78-7
Synonymsesomeprazole sodium; Esomeprazole (sodium); Natrium-5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-id; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt; Sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide; sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide; (S)-OMeprazole sodiuM; odiuM (R)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide; 5-méthoxy-2-{(S)-[(4-méthoxy-3,5-diméthylpyridin-2-yl)méthyl]sulfinyl}benzimidazol-1-ide de sodium; SodiuM (S)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide; 1H-BENZIMIDAZOLE,5-METHOXY-2-[[(4-METHOXY-3
Molecular FormulaC17H18N3NaO3S
Molecular Weight367.40
Boiling Point600ºC at 760 mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 161796-78-7 |
| Catalog No. | 2A-9060878 |
| Chinese Name | 埃索美拉唑钠 |
| Synonyms | esomeprazole sodium; Esomeprazole (sodium); Natrium-5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-id; 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl-1H-benzimidazole sodium salt; Sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide; sodium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide; (S)-OMeprazole sodiuM; odiuM (R)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide; 5-méthoxy-2-{(S)-[(4-méthoxy-3,5-diméthylpyridin-2-yl)méthyl]sulfinyl}benzimidazol-1-ide de sodium; SodiuM (S)-6-Methoxy-2-(((4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl)sulfinyl)benzo[d]iMidazol-1-ide; 1H-BENZIMIDAZOLE,5-METHOXY-2-[[(4-METHOXY-3 |
| Molecular Formula | C17H18N3NaO3S |
| Molecular Weight | 367.40 |
| Boiling Point | 600ºC at 760 mmHg |
| Appearance | solid |
| Storage Condition | 2-8°C |
| Application | Esomeprazole sodium salt is a proton pump inhibitor that can reduce acid secretion by inhibiting H+/K+ ATPase in gastric parietal cells. |
| HTC | 2933990090 |
| SMILES | COc1ccc2nc(S(=O)Cc3ncc(C)c(OC)c3C)[nH]c2c1.[Na] |
| InChI | 1S/C17H20N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8,17,19H,9H2,1-4H3;/q-1;+1/t17?,24-;/m0./s1 |
| InChI Key | ALGZIPAMEDTMAM-DPGOWHRRSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/60878_1_161796_78_7.pdf |
| Use of | Properties Name Esomeprazole sodium Synonym More Synonyms Esomeprazole sodium Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump Research Areas >> Others References [1]. Sandstr?m M, Davidson G, Tolia V et al. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age. Clin Ther. 2012 Aug;34(8):1828-38. [2]. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. [3]. Thomas C Kupiec, Vasileios Aloumanis, Michel Ben, et al. Physical and Chemical Stability of Esomeprazole Sodium Solutions. Ann Pharmacother. September 2008 ,42 ( 9 ):1247-1251. [4]. Esomeprazole Chemical & Physical Properties Molecular Formula C17H18N3NaO3S Exact Mass 367.096649 PSA 85.45000 LogP 3.55120 InChIKey HVAJOLFRLWQQQL-JIDHJSLPSA-N Safety Information Hazard Codes Xi HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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