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GSK-2126458

Name: GSK-2126458
Brand: 2A Biotech
SKU: 2A-9060224

CAS Number1086062-66-9

Synonyms2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide; 2,4-Difluoro-N-{2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl}benzenesulfonamide; GSK2126458; Omipalisib; gsk2126458 (gsk458); 2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide; GSK 2126458; gsk-212; GSK458

Molecular FormulaC25H17F2N5O3S

Molecular Weight505.50

Purity≥98 (HPLC)%

Density1.5±0.1 g/cm3

Boiling Point715.6±70.0 °C at 760 mmHg

Melting Point187-189℃

Appearancepowder

MSDSChinese English

Cat. No.: 2A-9060224 Purity: ≥98 (HPLC)%

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Quality Control of [ 1086062-66-9 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	1086062-66-9
Catalog No.	2A-9060224
Chinese Name	奥米利塞
Synonyms	2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide; 2,4-Difluoro-N-{2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl}benzenesulfonamide; GSK2126458; Omipalisib; gsk2126458 (gsk458); 2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide; GSK 2126458; gsk-212; GSK458
Molecular Formula	C25H17F2N5O3S
Molecular Weight	505.50
Purity	≥98 (HPLC)
Density	1.5±0.1 g/cm3
Boiling Point	715.6±70.0 °C at 760 mmHg
Melting Point	187-189℃
Appearance	powder
Storage Condition	-20℃
Application	Omipalisib (GSK2126458) is a highly selective and potent PI3K inhibitor that inhibits the activity of p110α/β/δ/γ, mTORC1/2, with Ki values of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM re
MDL Number	MFCD16038929
SMILES	FC(C=C1F)=CC=C1S(NC2=CC(C3=CC4=C(C5=CN=NC=C5)C=CN=C4C=C3)=CN=C2OC)(=O)=O
InChI	1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3
InChI Key	CGBJSGAELGCMKE-UHFFFAOYSA-N
NACRES Code	NA.77
UNSPSC	12352200
Transport Info	Product name: GSK2126458(GSK458)

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GSK-2126458

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