
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1146699-66-2 |
| Catalog No. | 2A-9060222 |
| Chinese Name | 塞来西布 |
| Synonyms | BMS-708163; Avagacestat |
| Molecular Formula | C20H17ClF4N4O4S |
| Molecular Weight | 520.89 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 652.3±65.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | BMS-708163 is a potent γ-secretase inhibitor, inhibiting the production of Aβ42 and Aβ40, with IC50 values of 0.27 nM and 0.30 nM, respectively; BMS-708163 also inhibits Notch intracellular domain ( |
| MDL Number | C20H17ClF4N4O4S |
| SMILES | NC(=O)C(CCC(F)(F)F)N(Cc1ccc(-c2ncon2)cc1F)S(=O)(=O)c1ccc(Cl)cc1 |
| InChI Key | XEAOPVUAMONVLA-QGZVFWFLSA-N |
| MSDS | msds/60222_1_1146699_66_2.pdf |
| Transport Info | Product Name: Avagacestat |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| N-Ethyl-4-methoxybenzylamine | 22993-76-6 | 2A-9060197 |
| ETHYL 4-CHLOROPHENYLACETATE | 14062-24-9 | 2A-9060198 |
| CHEMBRDG-BB 6644827 | 437650-06-1 | 2A-9060199 |
| POLYDIMETHYLSILOXANE | 8050-81-5 | 2A-9060219 |
| Unii-U2Y5ofn795 | 649735-63-7 | 2A-9060221 |
| GSK-2126458 | 1086062-66-9 | 2A-9060224 |
| HYDRASTININE HCL(RG) | 4884-68-8 | 2A-9060225 |
| SGX-523 | 1022150-57-7 | 2A-9060226 |
| PD04217903 | 956905-27-4 | 2A-9060227 |
| CRA-02478 | 783355-60-2 | 2A-9060228 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA