BMS-708163 structure, CAS 1146699-66-2

BMS-708163

CAS Number1146699-66-2

SynonymsBMS-708163; Avagacestat

Molecular FormulaC20H17ClF4N4O4S

Molecular Weight520.89

Purity

Density1.5±0.1 g/cm3

Boiling Point652.3±65.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9060222 Purity:
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Quality Control of [ 1146699-66-2 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number1146699-66-2
Catalog No.2A-9060222
Chinese Name塞来西布
SynonymsBMS-708163; Avagacestat
Molecular FormulaC20H17ClF4N4O4S
Molecular Weight520.89
Density1.5±0.1 g/cm3
Boiling Point652.3±65.0 °C at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationBMS-708163 is a potent γ-secretase inhibitor, inhibiting the production of Aβ42 and Aβ40, with IC50 values ​​of 0.27 nM and 0.30 nM, respectively; BMS-708163 also inhibits Notch intracellular domain (
MDL NumberC20H17ClF4N4O4S
SMILESNC(=O)C(CCC(F)(F)F)N(Cc1ccc(-c2ncon2)cc1F)S(=O)(=O)c1ccc(Cl)cc1
InChI KeyXEAOPVUAMONVLA-QGZVFWFLSA-N
MSDSmsds/60222_1_1146699_66_2.pdf
Transport InfoProduct Name: Avagacestat
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