Neratinib

Name: Neratinib
Brand: 2A Biotech
SKU: 2A-9057939

CAS Number698387-09-6

SynonymsHKI 272; S2150_Selleck; Neratinib(HKI-272); [2H]-Neratinib; Neratinib

Molecular FormulaC30H29ClN6O3

Molecular Weight557.04

Purity≥98 (HPLC)%

Density1.3±0.1 g/cm3

Boiling Point757.0±60.0 °C at 760 mmHg

Melting Point184 °C

Appearancepowder

Cat. No.: 2A-9057939 Purity: ≥98 (HPLC)%

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Quality Control of [ 698387-09-6 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	698387-09-6
Catalog No.	2A-9057939
Chinese Name	来那替尼
Synonyms	HKI 272; S2150_Selleck; Neratinib(HKI-272); [2H]-Neratinib; Neratinib
Molecular Formula	C30H29ClN6O3
Molecular Weight	557.04
Purity	≥98 (HPLC)
Density	1.3±0.1 g/cm3
Boiling Point	757.0±60.0 °C at 760 mmHg
Melting Point	184 °C
Appearance	powder
Storage Condition	<0°C; avoid heating
Application	Neratinib is an orally available, irreversible tyrosine kinase inhibitor that inhibits the activities of HER2 and EGFR with IC50 values of 59 nM and 92 nM respectively.
HTC	29334900
MDL Number	MFCD09752958
SMILES	CN(C)C/C=C/C(NC(C=C1C(NC2=CC(Cl)=C(C=C2)OCC3=NC=CC=C3)=C4C#N)=C(C=C1N=C4)OCC)=O
InChI Key	JWNPDZNEKVCWMY-VQHVLOKHSA-N
NACRES Code	NA.21
MSDS	msds/57939_1_698387_09_6.pdf
Transport Info	Product name: Neratinib (HKI-272)

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