CAS Number260367-12-2
SynonymsFmoc-O1Pen-OH; (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)acetic acid; {2-[9H-Fluoren-9-yl(methoxycarbonyl)amino]ethoxy}acetic acid; 2-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)ethoxy)acetic acid
Molecular FormulaC19H19O5N1
Molecular Weight341.36
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point563.8±50.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 260367-12-2 |
| Catalog No. | 2A-9056102 |
| Chinese Name | FMOC- 5-氨基-3-氧戊酸 |
| Synonyms | Fmoc-O1Pen-OH; (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)acetic acid; {2-[9H-Fluoren-9-yl(methoxycarbonyl)amino]ethoxy}acetic acid; 2-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)ethoxy)acetic acid |
| Molecular Formula | C19H19O5N1 |
| Molecular Weight | 341.36 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 563.8±50.0 °C at 760 mmHg |
| Storage Condition | 2-8°C, dry and sealed |
| Application | Fmoc-NH-PEG1-CH2COOH is a degradable ADC linker for antibody drug conjugate (ADC) synthesis. |
| HTC | 2924299090 |
| MDL Number | MFCD06796876 |
| SMILES | O=C(O)COCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
| InChI Key | LBVXPUINIMIGAU-UHFFFAOYSA-N |
| MSDS | msds/56102_1_260367_12_2.pdf |
| Bioactivity | Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 563.8±50.0 °C at 760 mmHg Molecular Formula C19H19NO5 Molecular Weight 341.358 Flash Point 294.8±30.1 °C Exact Mass 341.126312 PSA 84.86000 LogP 3.18 Vapour Pressure 0.0±1.6 mmHg at 25°C Index of Refraction 1.630 InChIKey LBVXPUINIMIGAU-UHFFFAOYSA-N SMILES O=C(O)COCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
| Use of | Properties Name 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]acetic acid Synonym More Synonyms Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Lorenzo Benatuil, et al. Anti-cd98 antibodies and antibody drug conjugates. WO2017214456A. Chemical & Physical Properties Molecular Formula C19H19NO5 Exact Mass 341.126312 PSA 84.86000 Index of Refraction 1.630 InChIKey LBVXPUINIMIGAU-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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