CAS Number226256-56-0
SynonymsUnii-uaz6V7728s; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluormethyl)phenyl]propan-1-amin; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine; Regpara; Mimpara; N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine; Cinacelcet HCl; AMG 073; AMG073; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine; N-[(1R)-1-(Naphthalen-1-yl)ethyl]-3-[3-(trifluormethyl)phenyl]propan-1-amin; Cinacalcet; KRN 1493; Sensipar; AMG-073
Molecular FormulaC22H22N1F3
Molecular Weight357.42
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point440.9±45.0 °C at 760 mmHg
Appearanceyellow oily
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 226256-56-0 |
| Catalog No. | 2A-9055833 |
| Chinese Name | 西那卡塞 |
| Synonyms | Unii-uaz6V7728s; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluormethyl)phenyl]propan-1-amin; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine; Regpara; Mimpara; N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine; Cinacelcet HCl; AMG 073; AMG073; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine; N-[(1R)-1-(Naphthalen-1-yl)ethyl]-3-[3-(trifluormethyl)phenyl]propan-1-amin; Cinacalcet; KRN 1493; Sensipar; AMG-073 |
| Molecular Formula | C22H22N1F3 |
| Molecular Weight | 357.42 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 440.9±45.0 °C at 760 mmHg |
| Appearance | yellow oily |
| Storage Condition | Refrigerator |
| Application | Cinacalcet is an orally available Ca receptor (CaR) agonist used to treat cardiovascular disease. |
| HTC | 2921499090 |
| MDL Number | MFCD09840270 |
| SMILES | CC(NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 |
| InChI Key | VDHAWDNDOKGFTD-MRXNPFEDSA-N |
| MSDS | msds/55833_1_226256_56_0.pdf |
| Use of | Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment. Properties Name cinacalcet Synonym More Synonyms Cinacalcet Biological Activity Description Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment. Related Catalog Signaling Pathways >> GPCR/G Protein >> CaSR Research Areas >> Cardiovascular Disease References [1]. Colloton M, et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int. 2005 Feb;67(2):467-76. [2]. D.A. Bushinsky, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92. Chemical & Physical Properties Molecular Formula C22H22F3N Exact Mass 357.170441 PSA 12.03000 Index of Refraction 1.563 InChIKey VDHAWDNDOKGFTD-MRXNPFEDSA-N Storage condition Refrigerator Safety Information HS Code 2921499090 Precursor & DownStream Precursor 9 CAS#:1073144-62-3 (1R)-1-(naphtha... CAS#:21172-43-0 Methanesulfonic... CAS#:1204313-93-8 (R)-4-nitro-N-(... CAS#:1095393-66-0 (R,E)-N-(1-(nap... DownStream 1 CAS#:364782-34-3 Cinacalcet hydr... |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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