CAS Number66722-44-9
Synonyms1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol; (±)-1-[p-(2-Isopropoxyethoxymethyl)phenoxy]-3-(isopropylamino)-2-propanol; 1-(propan-2-ylamino)-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol; Bisoprolol; 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol; MFCD00865795; 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol; (±)-1-[[a-(2-Isopropoxyethoxy)-p-tolyl]oxy]-3-(isopropylamino)-2-propanol; 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol; 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol; 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)-2-propanol
Molecular FormulaC18H31NO4
Molecular Weight325.443
Purity98.00%
Density1.0±0.1 g/cm3
Boiling Point445.0±45.0 °C at 760 mmHg
Appearanceyellow oily
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 66722-44-9 |
| Catalog No. | 2A-9046471 |
| Chinese Name | 比索洛尔 |
| Synonyms | 1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol; (±)-1-[p-(2-Isopropoxyethoxymethyl)phenoxy]-3-(isopropylamino)-2-propanol; 1-(propan-2-ylamino)-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol; Bisoprolol; 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol; MFCD00865795; 1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol; (±)-1-[[a-(2-Isopropoxyethoxy)-p-tolyl]oxy]-3-(isopropylamino)-2-propanol; 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol; 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol; 1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)-2-propanol |
| Molecular Formula | C18H31NO4 |
| Molecular Weight | 325.443 |
| Purity | 98.00 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 445.0±45.0 °C at 760 mmHg |
| Appearance | yellow oily |
| Storage Condition | Combustible; combustion produces toxic nitrogen ox |
| Application | Bisoprolol is a potent, selective, orally active β1-adrenergic receptor blocker. Bisoprolol has minimal activity at beta2 receptors and is used in the study of hypertension, coronary artery disease, a |
| HTC | 2922509090 |
| PubChem ID | 9070 |
| SMILES | CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1 |
| InChI | InChI=1S/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3 |
| InChI Key | VHYCDWMUTMEGQY-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/46471_1_66722_44_9.pdf |
| Use of | Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. Properties Articles18 Name bisoprolol Synonym More Synonyms Bisoprolol Biological Activity Description Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor β1-adrenergic receptor[1] References [1]. Jillian G Baker, et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22. [2]. Maria Hoeltzenbein, et al. Pregnancy outcome after first trimester exposure to bisoprolol: an observational cohort study. J Hypertens. 2018 Oct;36(10):2109-2117. Chemical & Physical Properties Molecular Formula C18H31NO4 Exact Mass 325.225311 PSA 59.95000 Index of Refraction 1.500 InChIKey VHYCDWMUTMEGQY-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 2-Propanol, 1-(4-((2-(1-methylethoxy)ethoxy)methyl)phenoxy)-3-((1 -methylethyl)amino)- CAS REGISTRY NUMBER : 66722-44-9 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C18-H31-N-O4 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Human - man DOSE/DURATION : TOXIC EFFECTS : Cardiac - change in rate REFERENCE : HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 9,255,1990 Safety Information Signal Word Warning Hazard Statements H302 Hazard Codes Xi Safety Phrases S26-S36 RIDADR NONH for all modes of transport RTECS UB8380000 HS Code 2922509090 |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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