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Sodium L-ascorbyl-2-phosphate structure, CAS 66170-10-3

Sodium L-ascorbyl-2-phosphate

CAS Number66170-10-3

SynonymsTrisodium (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-oxido-2-oxo-2,5-dihydro-3-furanyl phosphate; 2-Phospho-L-ascorbic acid trisodium salt; MFCD04038081

Molecular FormulaC6H6Na3O9P

Molecular Weight322.05 (anhydrous basis)

Purity≥95.0 (HPLC)%

Density

Boiling Point

Melting Point260 °C

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9046390 Purity: ≥95.0 (HPLC)%
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Quality Control of [ 66170-10-3 ] Purity: ≥95.0 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number66170-10-3
Catalog No.2A-9046390
Chinese Name维生素C磷酸酯钠
SynonymsTrisodium (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-oxido-2-oxo-2,5-dihydro-3-furanyl phosphate; 2-Phospho-L-ascorbic acid trisodium salt; MFCD04038081
Molecular FormulaC6H6Na3O9P
Molecular Weight322.05 (anhydrous basis)
Purity≥95.0 (HPLC)
Melting Point260 °C
Appearancepowder
Storage ConditionStore in an airtight container in a cool, dry plac
Application2-Phospho-L-ascorbic acid trisodium salt is an antioxidant that promotes the production of hepatocyte growth factor (HGF).
HTC2932209090
PubChem ID16049700
MDL NumberMFCD03095479
SMILES[Na+].[Na+].[Na+].[P](=O)([O-])([O-])OC1=C([C@H](OC1=O)[C@@H](O)CO)[O-]
InChI1S/C6H9O9P.3Na/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;/h2,4,7-9H,1H2,(H2,11,12,13);;;/q;3*+1/p-3/t2-,4+;;;/m0.../s1
InChI KeyYRWWOAFMPXPHEJ-OFBPEYICSA-K
NACRES CodeNA.79
UNSPSC12352205
Hazard Symbolstransportation
MSDSmsds/46390_1_66170_10_3.pdf
Bioactivity2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. Related Catalog Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR In Vitro 2-Phospho-L-ascorbic acid (Asc 2-P) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 2-Phospho-L-ascorbic acid is a stable derivative of L-ascorbic acid (AA) and possesses similar biological properties as AA. AA and Asc-2P regulate a number of biological processes[1]. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced DKK-1 mRNA expression in DPCs is significantly attenuated. It is also found that DKK-1 promoter activity is increased by DHT treatmen. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced activation of luciferase activity is significantly repressed[2]. References [1]. Bae SH, et al. L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors. 2015 Apr;33(2):71-8. [2]. Kwack MH, et al. L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human balding dermal papilla cells. Exp Dermatol. 2010 Dec;19(12):1110-2. Chemical & Physical Properties Melting Point 84 °C Molecular Formula C6H6Na3O9P Molecular Weight 322.049 Exact Mass 321.944244 PSA 172.05000 InChIKey ABTBLEGNFLLCMG-OFBPEYICSA-N SMILES O=C1OC(C(O)CO)C(O)=C1OP(=O)(O)O.[Na].[Na].[Na]
Use of2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. Properties Name Sodium L-Ascorbyl-2-Phosphate Synonym More Synonyms 2-Phospho-L-ascorbic acid trisodium salt Biological Activity Description 2-Phospho-L-ascorbic acid trisodium salt acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. Related Catalog Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Met/HGFR References [1]. Bae SH, et al. L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors. 2015 Apr;33(2):71-8. [2]. Kwack MH, et al. L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human balding dermal papilla cells. Exp Dermatol. 2010 Dec;19(12):1110-2. Chemical & Physical Properties Molecular Formula C6H6Na3O9P Exact Mass 321.944244 PSA 172.05000 InChIKey ABTBLEGNFLLCMG-OFBPEYICSA-N SMILES O=C1OC(C(O)CO)C(O)=C1OP(=O)(O)O.[Na].[Na].[Na]
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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