EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Nalmefene
Nalmefene structure, CAS 55096-26-9

Nalmefene

CAS Number55096-26-9

SynonymsArthene; Nalmefenum; Nalmetrenum; Alcofene; Nalmetreno; 6-desoxy-6-methylenenaltrexone; Nalmetrene; Revex; nalmefene; Cervene

Molecular FormulaC21H25NO3

Molecular Weight339.43

Purity98.00%

Density

Boiling Point

Melting Point188 - 190ºC

Flash Point

Appearance

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9044330 Purity: 98.00%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 55096-26-9 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number55096-26-9
Catalog No.2A-9044330
Chinese Name纳美芬
SynonymsArthene; Nalmefenum; Nalmetrenum; Alcofene; Nalmetreno; 6-desoxy-6-methylenenaltrexone; Nalmetrene; Revex; nalmefene; Cervene
Molecular FormulaC21H25NO3
Molecular Weight339.43
Purity98.00
Melting Point188 - 190ºC
Storage Condition2-8°C
ApplicationNalmefene is a long-acting opioid agent (MOR and DOR antagonist) and a partial KOR agonist. Nalmefene is used to treat opioid overdose and alcohol dependence.
PubChem ID10227
SMILESC=C1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5
InChIInChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1
InChI KeyWJBLNOPPDWQMCH-MBPVOVBZSA-N
Hazard Symbolstransportation
BioactivityNalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease Target MOR, DOR, KOR[1] References [1]. Wang DS, et al. Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J Emerg Med. 1998 May-Jun;16(3):471-5. [2]. Mann K, et al. Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy. Eur Neuropsychopharmacol. 2016 Dec;26(12):1941-1949. Chemical & Physical Properties Melting Point 188 - 190ºC Molecular Formula C21H25NO3 Molecular Weight 339.43 Exact Mass 339.18300 PSA 52.93000 LogP 2.45040 InChIKey WJBLNOPPDWQMCH-MBPVOVBZSA-N SMILES C=C1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 Storage condition 2-8°C
Use ofNalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence[1]. Properties Articles39 Name (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol Synonym More Synonyms Nalmefene Biological Activity Description Nalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence[1]. Related Catalog Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease MOR, DOR, KOR[1] References [1]. Wang DS, et al. Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J Emerg Med. 1998 May-Jun;16(3):471-5. [2]. Mann K, et al. Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy. Eur Neuropsychopharmacol. 2016 Dec;26(12):1941-1949. Chemical & Physical Properties Molecular Formula C21H25NO3 Exact Mass 339.18300 PSA 52.93000 LogP 2.45040 InChIKey WJBLNOPPDWQMCH-MBPVOVBZSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
Related Products in Specialty Chemicals
3-Methyl-5-phenylpentan-1-ol55066-48-32A-9044321
Glycerol phosphate disodium salt hydrate55073-41-12A-9044323
1-(4-Chlorophenyl)piperazin-2-one55083-85-72A-9044327
5-Chloropentyl benzoate55092-47-22A-9044328
2,3,5-Tri-O-benzyl-D-ribonolactone55094-52-52A-9044329
2-Chloro-6-fluorobenzyl chloride55117-15-22A-9044333
Calcium trifluoromethanesulfonate55120-75-72A-9044334
9-Bromo-9-phenylfluorene55135-66-52A-9044337
Nickel methane sulfonate55136-38-42A-9044338
2-Ethoxynaphthalene-1-carbonyl chloride55150-29-32A-9044343
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA