CAS Number54149-17-6
Synonyms1-Bromo-(2-methoxyethoxy)ethane; 1-Bromo-2-(2-methoxyethoxy)ethane; EINECS 259-000-6; MFCD00000238; 1-(2-Bromoethoxy)-2-methoxyethane
Molecular FormulaCH3(OCH2CH2)2Br
Molecular Weight183.04
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point184.4±15.0 °C at 760 mmHg
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 54149-17-6 |
| Catalog No. | 2A-9044142 |
| Chinese Name | 1-溴-2-(2-甲氧基乙氧基)乙烷 |
| Synonyms | 1-Bromo-(2-methoxyethoxy)ethane; 1-Bromo-2-(2-methoxyethoxy)ethane; EINECS 259-000-6; MFCD00000238; 1-(2-Bromoethoxy)-2-methoxyethane |
| Molecular Formula | CH3(OCH2CH2)2Br |
| Molecular Weight | 183.04 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 184.4±15.0 °C at 760 mmHg |
| Storage Condition | Sealed in a cool, dry environment |
| Application | m-PEG2-Br is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2909199090 |
| PubChem ID | 24869136 |
| SMILES | COCCOCCBr |
| InChI | InChI=1S/C5H11BrO2/c1-7-4-5-8-3-2-6/h2-5H2,1H3 |
| InChI Key | HUXJXNSHCKHFIL-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 184.4±15.0 °C at 760 mmHg Molecular Formula C5H11BrO2 Molecular Weight 183.044 Flash Point 73.9±0.0 °C Exact Mass 181.994232 PSA 18.46000 LogP 0.54 Vapour Pressure 1.0±0.3 mmHg at 25°C Index of Refraction 1.445 InChIKey HUXJXNSHCKHFIL-UHFFFAOYSA-N SMILES COCCOCCBr Storage condition Refrigerator (+4°C) |
| Use of | m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 1-Bromo-2-(2-methoxyethoxy)ethane Synonym More Synonyms m-PEG2-Br Biological Activity Description m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C5H11BrO2 Exact Mass 181.994232 PSA 18.46000 Index of Refraction 1.445 InChIKey HUXJXNSHCKHFIL-UHFFFAOYSA-N SMILES COCCOCCBr |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 90.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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