CAS Number51644-96-3
SynonymsN-Boc-cadaverine; N-(5-Aminopentyl)carbamic Acid tert-Butyl Ester; tert-Butyl (5-aminopentyl)carbamate; N-(tert-Butoxycarbonyl)-1,5-pentanediamine; N-Boc-1,5-diaminopentane; tert-butyl N-(5-aminopentyl)carbamate; N-Boc-1,5-pentanediamine; 2-Methyl-2-propanyl (5-aminopentyl)carbamate; Carbamic acid, N-(5-aminopentyl)-, 1,1-dimethylethyl ester; N-(5-Aminoamyl)carbamic Acid tert-Butyl Ester; MFCD00210020; N-(tert-Butoxycarbonyl)-1,5-diaminopentane
Molecular Formula(CH)3COCONH(CH2)5NH2
Molecular Weight202.29
Purity≥97.0 (NT)%
Density1.0±0.1 g/cm3
Boiling Point309.2±25.0 °C at 760 mmHg
AppearanceLiquid;Colorless to Light yellow clear liquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51644-96-3 |
| Catalog No. | 2A-9043544 |
| Chinese Name | N-(5-氨基戊基)氨基甲酸叔丁酯 |
| Synonyms | N-Boc-cadaverine; N-(5-Aminopentyl)carbamic Acid tert-Butyl Ester; tert-Butyl (5-aminopentyl)carbamate; N-(tert-Butoxycarbonyl)-1,5-pentanediamine; N-Boc-1,5-diaminopentane; tert-butyl N-(5-aminopentyl)carbamate; N-Boc-1,5-pentanediamine; 2-Methyl-2-propanyl (5-aminopentyl)carbamate; Carbamic acid, N-(5-aminopentyl)-, 1,1-dimethylethyl ester; N-(5-Aminoamyl)carbamic Acid tert-Butyl Ester; MFCD00210020; N-(tert-Butoxycarbonyl)-1,5-diaminopentane |
| Molecular Formula | (CH)3COCONH(CH2)5NH2 |
| Molecular Weight | 202.29 |
| Purity | ≥97.0 (NT) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 309.2±25.0 °C at 760 mmHg |
| Appearance | Liquid;Colorless to Light yellow clear liquid |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | PROTAC Linker 23 is a PROTAC connection bridge, belonging to the alkyl chain category. PROTAC Linker 23 can be used to synthesize a range of PROTAC molecules. PROTAC molecules contain two different li |
| HTC | 2924199090 |
| PubChem ID | 57647414 |
| MDL Number | MFCD00210020 |
| SMILES | NCCCCCNC(OC(C)(C)C)=O |
| InChI | 1S/C10H22N2O2/c1-10(2,3)14-9(13)12-8-6-4-5-7-11/h4-8,11H2,1-3H3,(H,12,13) |
| InChI Key | DPLOGSUBQDREOU-UHFFFAOYSA-N |
| Beilstein/REAXYS | 3603658 |
| NACRES Code | NA.22 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/43544_1_51644_96_3.pdf |
| Bioactivity | PROTAC Linker 23 is a PROTAC linker, which refers to the alkyl chain composition. PROTAC Linker 23 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target Alkyl-Chain References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 309.2±25.0 °C at 760 mmHg Molecular Formula C10H22N2O2 Molecular Weight 202.294 Flash Point 140.8±23.2 °C Exact Mass 202.168121 PSA 64.35000 LogP 1.29 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.458 InChIKey DPLOGSUBQDREOU-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCCCCN Storage condition 2-8°C |
| Use of | Properties Name N-(5-Aminoamyl)Carbamic Acid Tert-Butyl Ester Synonym More Synonyms N-Boc-1,5-diaminopentane Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl-Chain References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C10H22N2O2 Exact Mass 202.168121 PSA 64.35000 Index of Refraction 1.458 InChIKey DPLOGSUBQDREOU-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCCCCN |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2735 International Dangerous Regulations for sea transport: 2735 International Dangerous Regulations for air transport: 2735 14.2 United Nations shipping name European Land Transport Dangerous Regulations: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-1,5-diaminopentane) IMDG Code: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-1,5-diaminopentane) International air transport hazard regulations: Amines, liquid, corrosive, n.o.s. (N-Boc-1,5-diaminopentane) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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