CAS Number51857-17-1
SynonymsN-(tert-Butoxycarbonyl)-1,6-diaminohexane; N-Boc-1,6-hexanediamine; tert-Butyl (6-aminohexyl)carbamate; N-Boc-1,6-Diaminohexane; N-(6-Aminohexyl)carbamic Acid tert-Butyl Ester; tert-butyl N-(6-aminohexyl)carbamate; Carbamic acid, N-(6-aminohexyl)-, 1,1-dimethylethyl ester; MFCD00671489; 2-Methyl-2-propanyl (6-aminohexyl)carbamate; N-(tert-Butoxycarbonyl)-1,6-hexanediamine
Molecular FormulaC11H24N2O2
Molecular Weight216.32
Purity≥98.0 (NT)%
Density1.0±0.1 g/cm3
Boiling Point325.3±25.0 °C at 760 mmHg
Appearanceliquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51857-17-1 |
| Catalog No. | 2A-9043609 |
| Chinese Name | N-Boc-1,6-二氨基己烷 |
| Synonyms | N-(tert-Butoxycarbonyl)-1,6-diaminohexane; N-Boc-1,6-hexanediamine; tert-Butyl (6-aminohexyl)carbamate; N-Boc-1,6-Diaminohexane; N-(6-Aminohexyl)carbamic Acid tert-Butyl Ester; tert-butyl N-(6-aminohexyl)carbamate; Carbamic acid, N-(6-aminohexyl)-, 1,1-dimethylethyl ester; MFCD00671489; 2-Methyl-2-propanyl (6-aminohexyl)carbamate; N-(tert-Butoxycarbonyl)-1,6-hexanediamine |
| Molecular Formula | C11H24N2O2 |
| Molecular Weight | 216.32 |
| Purity | ≥98.0 (NT) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 325.3±25.0 °C at 760 mmHg |
| Appearance | liquid |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Packaging | III |
| Application | NH2-C6-NH-Boc is a PROTAC linker, belonging to the alkyl/ether class. NH2-C6-NH-Boc is a Mcl-1 inhibitor that can be used in PROTAC-based technology. |
| HTC | 2924199090 |
| PubChem ID | 57652779 |
| MDL Number | MFCD00671489 |
| SMILES | NCCCCCCNC(OC(C)(C)C)=O |
| InChI | 1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14) |
| InChI Key | RVZPDKXEHIRFPM-UHFFFAOYSA-N |
| Beilstein/REAXYS | 2219107 |
| NACRES Code | NA.22 |
| UNSPSC | 12352116 |
| Hazard Symbols | 8 |
| MSDS | msds/43609_1_51857_17_1.pdf |
| Bioactivity | NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker References [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 325.3±25.0 °C at 760 mmHg Molecular Formula C11H24N2O2 Molecular Weight 216.320 Flash Point 150.5±23.2 °C Exact Mass 216.183777 PSA 64.35000 LogP 1.82 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.460 InChIKey RVZPDKXEHIRFPM-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCCCCCN |
| Use of | NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1]. Properties Name N-tert-Butoxycarbonyl-1,6-hexanediamine Synonym More Synonyms NH2-C6-NH-Boc Biological Activity Description NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker References Chemical & Physical Properties Molecular Formula C11H24N2O2 Exact Mass 216.183777 PSA 64.35000 Index of Refraction 1.460 InChIKey RVZPDKXEHIRFPM-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCCCCCN |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2735 International Dangerous Regulations for sea transport: 2735 International Dangerous Regulations for air transport: 2735 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-1,6-hexanediamine) IMDG Code: AMINES, LIQUID, CORROSIVE, N.O.S. (N-Boc-1,6-hexanediamine) International air transport hazard regulations: Amines, liquid, corrosive, n.o.s. (N-Boc-1,6-hexanediamine) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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