CAS Number51568-18-4
Synonyms4,6-Dioxoheptanoic acid; Succinylacetone; 4,6-DIOXOHEPTANOIC ACID
Molecular FormulaCH3COCH2COCH2CH2CO2H
Molecular Weight158.15
Purity98.00%
Density1.189 g/cm3
Boiling Point318.7ºC at 760 mmHg
Melting Point66-67 °C (lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51568-18-4 |
| Catalog No. | 2A-9043519 |
| Chinese Name | 4,6-二氧代庚酸 |
| Synonyms | 4,6-Dioxoheptanoic acid; Succinylacetone; 4,6-DIOXOHEPTANOIC ACID |
| Molecular Formula | CH3COCH2COCH2CH2CO2H |
| Molecular Weight | 158.15 |
| Purity | 98.00 |
| Density | 1.189 g/cm3 |
| Boiling Point | 318.7ºC at 760 mmHg |
| Melting Point | 66-67 °C (lit.) |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. |
| HTC | 2918300090 |
| PubChem ID | 24893433 |
| MDL Number | MFCD00002797 |
| SMILES | CC(=O)CC(=O)CCC(O)=O |
| InChI | 1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11) |
| InChI Key | WYEPBHZLDUPIOD-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352211 |
| Hazard Symbols | transportation |
| MSDS | msds/43519_1_51568_18_4.pdf |
| Bioactivity | 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Cardiovascular Disease Target Human Endogenous Metabolite In Vitro 4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture[1]. References [1]. Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90. Chemical & Physical Properties Density 1.189 g/cm3 Boiling Point 318.7ºC at 760 mmHg Melting Point 66-67ºC Molecular Formula C7H10O4 Molecular Weight 158.15200 Flash Point 160.8ºC Exact Mass 158.05800 PSA 71.44000 LogP 0.39940 Index of Refraction 1.455 InChIKey WYEPBHZLDUPIOD-UHFFFAOYSA-N SMILES CC(=O)CC(=O)CCC(=O)O Storage condition 2-8°C |
| Use of | 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. Properties Articles37 Name 4,6-dioxoheptanoic acid Synonym More Synonyms 4,6-Dioxoheptanoic acid Biological Activity Description 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Cardiovascular Disease Human Endogenous Metabolite In Vitro 4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture[1]. References [1]. Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90. Chemical & Physical Properties Molecular Formula C7H10O4 Exact Mass 158.05800 PSA 71.44000 LogP 0.39940 Index of Refraction 1.455 InChIKey WYEPBHZLDUPIOD-UHFFFAOYSA-N SMILES CC(=O)CC(=O)CCC(=O)O |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1-Aminonaphthalene-6-sulfonic acid | 51548-48-2 | 2A-9043512 |
| (Dimethylamino)acetyl chloride | 51552-16-0 | 2A-9043513 |
| 2-(Ethylamino)propiophenone hydrochloride | 51553-17-4 | 2A-9043514 |
| 1-(4-Bromophenyl)octane | 51554-93-9 | 2A-9043515 |
| Citronellyl nitrile | 51566-62-2 | 2A-9043518 |
| 9,10-Bis(phenylethynyl)-2-methylanthracene | 51580-23-5 | 2A-9043520 |
| Sodium dichloroisocyanurate dihydrate | 51580-86-0 | 2A-9043521 |
| 3-(2-Methylquinolin-1-ium-1-yl)propane-1-sulfonate | 51583-69-8 | 2A-9043524 |
| 2,3-Dimethylbenzylamine | 51586-20-0 | 2A-9043526 |
| Butyltin oxide | 51590-67-1 | 2A-9043528 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS