Miconazole structure, CAS 22916-47-8

Miconazole

CAS Number22916-47-8

Synonyms1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; EINECS 245-324-5; 1-[2,4-Dichloro-b-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole; Daktarin IV; MFCD00216019; MONISTAT IV; Minostate; 1-(2,4-dichloro-β-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole; Desenex; Miconozole; (±)-Miconazole; Monistat; mjr1762; 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole; 1-{2-[(2,4-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; micronazol; Miconazole; Zeasorb-AF

Molecular FormulaC18H14Cl4N2O

Molecular Weight416.13

Purity98.00%

Density1.4±0.1 g/cm3

Boiling Point555.1±50.0 °C at 760 mmHg

Melting Point159-163ºC

Flash Point

Appearancewhite powder

EINECS

MSDSChineseEnglish

Symbol6.1(b)

Signal WordWarning

Cat. No.: 2A-9039106 Purity: 98.00%
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Quality Control of [ 22916-47-8 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number22916-47-8
Catalog No.2A-9039106
Chinese Name咪康唑
Synonyms1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; EINECS 245-324-5; 1-[2,4-Dichloro-b-[(2,4-dichlorobenzyl)oxy]phenethyl]imidazole; Daktarin IV; MFCD00216019; MONISTAT IV; Minostate; 1-(2,4-dichloro-β-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole; Desenex; Miconozole; (±)-Miconazole; Monistat; mjr1762; 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole; 1-{2-[(2,4-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; micronazol; Miconazole; Zeasorb-AF
Molecular FormulaC18H14Cl4N2O
Molecular Weight416.13
Purity98.00
Density1.4±0.1 g/cm3
Boiling Point555.1±50.0 °C at 760 mmHg
Melting Point159-163ºC
Appearancewhite powder
PackagingIII
ApplicationMiconazole (Monistat) is an imidazole antifungal agent.
HTC2933290090
SMILESClc1c(ccc(c1)Cl)C(OCc3c(cc(cc3)Cl)Cl)C[n]2cncc2
InChI1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2
InChI KeyBYBLEWFAAKGYCD-UHFFFAOYSA-N
NACRES CodeNA.24
UNSPSC41116107
Hazard Symbols6.1(b)
MSDSmsds/39106_1_22916_47_8.pdf
BioactivityMiconazole (Monistat) is an imidazole antifungal agent.Target: AntifungalMiconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process. From Wikipedia. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection References [1]. http://en.wikipedia.org/wiki/Miconazole Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 555.1±50.0 °C at 760 mmHg Melting Point 159-163ºC Molecular Formula C18H14Cl4N2O Molecular Weight 416.129 Flash Point 289.5±30.1 °C Exact Mass 413.986023 PSA 27.05000 LogP 5.93 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.625 InChIKey BYBLEWFAAKGYCD-UHFFFAOYSA-N SMILES Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
Use ofMiconazole (Monistat) is an imidazole antifungal agent.Target: AntifungalMiconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process. From Wikipedia. Properties Articles58 Name Miconazole Synonym More Synonyms Miconazole Biological Activity Description Miconazole (Monistat) is an imidazole antifungal agent.Target: AntifungalMiconazole is an imidazole antifungal agent, developed by Janssen Pharmaceutica, commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasite that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties. Miconazole is also used in Ektachrome film developing in the final rinse of the Kodak E-6 process and similar Fuji CR-56 process, replacing formaldehyde. Fuji Hunt also includes miconazole as a final rinse additive in their formulation of the C-41RA rapid access color negative developing process. From Wikipedia. Related Catalog Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection References [1]. http://en.wikipedia.org/wiki/Miconazole Chemical & Physical Properties Exact Mass 413.986023 PSA 27.05000 Index of Refraction 1.625 InChIKey BYBLEWFAAKGYCD-UHFFFAOYSA-N
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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