CAS Number25332-39-2
Synonymstrazolan; AzoNa; Trittico; BiMaran; Trazodone (hydrochloride); Mesyrel; Trazodone HCl; 2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one Hydrochloride; tombran; thombran; 2-{3-[4-(3-Chlorphenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-onhydrochlorid; MFCD00079603; Trazodone Hydrochloride; EINECS 246-855-5; 2-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo[4,3-a]pyridin-3(2H)-one Monohydrochloride; Molipaxin; kb-831; 2-{3-[4-(3-chlorophényl)pipérazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one chlorhydrate; af1161; Desyrel; Undepre
Molecular FormulaC19H23Cl2N5O
Molecular Weight408.325
Purity97%
Boiling Point528.5ºC at 760 mmHg
Melting Point223ºC
Appearancepowder | off-white
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 25332-39-2 |
| Catalog No. | 2A-9039710 |
| Chinese Name | 盐酸曲唑酮 |
| Synonyms | trazolan; AzoNa; Trittico; BiMaran; Trazodone (hydrochloride); Mesyrel; Trazodone HCl; 2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one Hydrochloride; tombran; thombran; 2-{3-[4-(3-Chlorphenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-onhydrochlorid; MFCD00079603; Trazodone Hydrochloride; EINECS 246-855-5; 2-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo[4,3-a]pyridin-3(2H)-one Monohydrochloride; Molipaxin; kb-831; 2-{3-[4-(3-chlorophényl)pipérazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one chlorhydrate; af1161; Desyrel; Undepre |
| Molecular Formula | C19H23Cl2N5O |
| Molecular Weight | 408.325 |
| Purity | 97 |
| Boiling Point | 528.5ºC at 760 mmHg |
| Melting Point | 223ºC |
| Appearance | powder | off-white |
| Water Solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 |
| Storage Condition | Place in a tight container and store in a cool, dr |
| Packaging | III |
| Application | Trazodone hydrochloride is a serotonin receptor antagonist and reuptake inhibitor that can act on anxiety disorders. |
| HTC | 2933990090 |
| SMILES | Cl.O=c1n(CCCN2CCN(c3cccc(Cl)c3)CC2)nc2ccccn12 |
| InChI | InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H |
| InChI Key | OHHDIOKRWWOXMT-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/39710_2_25332_39_2.pdf |
| Bioactivity | Chemical & Physical Properties |
| Use of | Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.Target: 5-HT ReceptorTrazodone is a triazolopyridine derivative, chemically and pharmacologically unrelated to other currently available antidepressants. Trazodone has been successfully used in a small number of patients with depression and pre-existing cardiovascular disease. trazodone has also been used as a hypnotic for psychotropic-induced or other insomnias with some success [1]. Trazodone is an effective hypnotic for patients with antidepressant-associated insomnia [2]. Trazodone may be helpful in men with erectile dysfunction (ED), possibly more so at higher doses, and in men with psychogenic ED. Future high-quality trials should compare trazodone with placebo and other therapies in men with depression and psychogenic ED [3]. Properties Articles38 Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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