CAS Number21343-40-8
Synonyms25-Hydroxy Vitamin D2; (3S,5Z,7E,20R,22E)-9,10-Secoergosta-5,7,10,22-tetraene-3,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3b,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3β,25-diol; Ercalcidiol,3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3,25-diol; EINECS 200-578-6; 25-Hydroxyvitamin D2; 25-Hydroxyvitamin D 2; 25-Hydroxyergocalciferol; 25-Hydroxyergocalciferol 25-Hydroxycalciferol; MFCD02683431; 25-Hydroxycalciferol; Ercalcidiol
Molecular FormulaC28H44O2
Molecular Weight412.65
Purity≥95.0 (HPLC)%
Density1.0±0.1 g/cm3
Boiling Point542.3±38.0 °C at 760 mmHg
Melting Point45-51ºC
Appearancecrystalline powder
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 21343-40-8 |
| Catalog No. | 2A-9038666 |
| Chinese Name | 25-羟基维生素 D2 |
| Synonyms | 25-Hydroxy Vitamin D2; (3S,5Z,7E,20R,22E)-9,10-Secoergosta-5,7,10,22-tetraene-3,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3b,25-diol; 9,10-Secoergosta-5,7,10(19),22-tetraene-3β,25-diol; Ercalcidiol,3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3,25-diol; EINECS 200-578-6; 25-Hydroxyvitamin D2; 25-Hydroxyvitamin D 2; 25-Hydroxyergocalciferol; 25-Hydroxyergocalciferol 25-Hydroxycalciferol; MFCD02683431; 25-Hydroxycalciferol; Ercalcidiol |
| Molecular Formula | C28H44O2 |
| Molecular Weight | 412.65 |
| Purity | ≥95.0 (HPLC) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 542.3±38.0 °C at 760 mmHg |
| Melting Point | 45-51ºC |
| Appearance | crystalline powder |
| Storage Condition | −20°C |
| Application | Ercalcidiol is a vitamin D2 metabolite that serves as an indicator of vitamin D nutritional status. |
| PubChem ID | 57647689 |
| MDL Number | MFCD02683431 |
| SMILES | [H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C |
| InChI | 1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1 |
| InChI Key | KJKIIUAXZGLUND-ICCVIKJNSA-N |
| Beilstein/REAXYS | 4716773 |
| NACRES Code | NA.28 |
| eCl@ss | 34058017 |
| UNSPSC | 12352205 |
| MSDS | msds/38666_1_21343_40_8.pdf |
| Bioactivity | Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease Natural Products >> Steroids Target Human Endogenous Metabolite In Vitro Differentiation between Ercalcidiol (25(OH)D2) and 25(OH)D3 is important for monitoring vitamin D therapy, as vitamin D2 is the predominant prescription form. The half-life of Ercalcidiol is shorter than that of 25(OH)D3 and it binds less well to the vitamin D binding protein, making it less potent and, therefore, required to be administered at much higher doses than vitamin D3. Some currently used assays have a diminished capacity to detect Ercalcidiol, which can lead to dangerous overdosing when attempting to monitor therapy with vitamin D2[2]. References [1]. Li L, et al. Performance evaluation of two immunoassays for 25-hydroxyvitamin D. J Clin Biochem Nutr. 2016 May;58(3):186-92. [2]. Newman MS, et al. A liquid chromatography/tandem mass spectrometry method for determination of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in dried blood spots: a potential adjunct to diabetes and cardiometabolic risk screening. J Diabetes Sci Technol Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 542.3±38.0 °C at 760 mmHg Melting Point 45-51ºC Molecular Formula C28H44O2 Molecular Weight 412.648 Flash Point 225.9±21.4 °C Exact Mass 412.334137 PSA 40.46000 LogP 7.56 Vapour Pressure 0.0±3.3 mmHg at 25°C Index of Refraction 1.543 InChIKey KJKIIUAXZGLUND-CDHMVDRZSA-N SMILES C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)C=CC(C)C(C)(C)O Storage condition −20°C |
| Use of | Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. Properties Articles47 Name 25-hydroxyvitamin D2 Synonym More Synonyms 25-Hydroxycalciferol Biological Activity Description Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status. Related Catalog Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Metabolic Disease Natural Products >> Steroids Human Endogenous Metabolite In Vitro Differentiation between Ercalcidiol (25(OH)D2) and 25(OH)D3 is important for monitoring vitamin D therapy, as vitamin D2 is the predominant prescription form. The half-life of Ercalcidiol is shorter than that of 25(OH)D3 and it binds less well to the vitamin D binding protein, making it less potent and, therefore, required to be administered at much higher doses than vitamin D3. Some currently used assays have a diminished capacity to detect Ercalcidiol, which can lead to dangerous overdosing when attempting to monitor therapy with vitamin D2[2]. References [1]. Li L, et al. Performance evaluation of two immunoassays for 25-hydroxyvitamin D. J Clin Biochem Nutr. 2016 May;58(3):186-92. [2]. Newman MS, et al. A liquid chromatography/tandem mass spectrometry method for determination of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in dried blood spots: a potential adjunct to diabetes and cardiometabolic risk screening. J Diabetes Sci Technol Chemical & Physical Properties Molecular Formula C28H44O2 Exact Mass 412.334137 PSA 40.46000 Index of Refraction 1.543 InChIKey KJKIIUAXZGLUND-CDHMVDRZSA-N |
| Transport Info | Product Name: 25-Hydroxyvitamin D₂ |
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