CAS Number23155-02-4
SynonymsVeramina; MFCD00242804; Fosfocina; [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid; phosphomycin; Fosfomycinum; FOSFOMYCIN; Fosfomicina; EINECS 245-463-1; Phosphonomycin; Fosfomycine
Molecular FormulaC3H7O4P
Molecular Weight182.02
Purity95.00%
Density1.561g/cm3
Boiling Point342.651ºC at 760 mmHg
Melting Point94ºC
EINECS247-409-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 23155-02-4 |
| Catalog No. | 2A-9039195 |
| Chinese Name | 磷霉素 |
| Synonyms | Veramina; MFCD00242804; Fosfocina; [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid; phosphomycin; Fosfomycinum; FOSFOMYCIN; Fosfomicina; EINECS 245-463-1; Phosphonomycin; Fosfomycine |
| Molecular Formula | C3H7O4P |
| Molecular Weight | 182.02 |
| Purity | 95.00 |
| Density | 1.561g/cm3 |
| Boiling Point | 342.651ºC at 760 mmHg |
| Melting Point | 94ºC |
| Application | Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can penetrate the blood-brain barrier and irreversibly inhibit the early stages of cell wall synthesis. Fosfomycin has antibacterial act |
| EINECS | 247-409-2 |
| HTC | 2931900090 |
| PubChem ID | 329754806 |
| MDL Number | MFCD22741288 |
| SMILES | [Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O |
| InChI | 1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1 |
| InChI Key | QZIQJIKUVJMTDG-JSTPYPERSA-L |
| Beilstein/REAXYS | 4604425 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/39195_1_23155_02_4.pdf |
| Use of | Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2]. Properties Name fosfomycin Synonym More Synonyms Fosfomycin Biological Activity Description Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47. [2]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31. 6(4):24. [3]. Inouye S, et al. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec. 5(12):941-50. Chemical & Physical Properties Molecular Formula C3H7O4P Exact Mass 138.00800 PSA 79.87000 Index of Refraction 1.486 InChIKey YMDXZJFXQJVXBF-STHAYSLISA-N SMILES CC1OC1P(=O)(O)O Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Phosphonic acid, (1,2-epoxypropyl)-, (1R,2S)-(-)- CAS REGISTRY NUMBER : 23155-02-4 BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C3-H7-O4-P MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T3OTJ BPQQO C1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Microorganism - not otherwise specified DOSE/DURATION : REFERENCE : MILEDM Microbios Letters. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1976- Volume(issue)/page/year: 8,27,1978 Safety Information HS Code 2931900090 Precursor & DownStream Precursor 3 CAS#:26016-99-9 Disodium phosph... CAS#:2041-14-7 (2-aminoethyl)p... CAS#:22987-21-9 2-HYDROXYETHYL ... DownStream 1 CAS#:32986-56-4 Tobramycin |
| Tax Rebate | 13.0% |
| Supervision | AB (Inbound cargo customs clearance form) |
| Related Products in Nutritional Ingredients | ||
|---|---|---|
| N-Acetyl-3,5-dinitro-L-tyrosine | 20767-00-4 | 2A-9038515 |
| 1-Pyrimidin-2-yl-[1,4]diazepane | 21279-57-2 | 2A-9038647 |
| 25-Hydroxyvitamin D2 | 21343-40-8 | 2A-9038666 |
| Hydroxocobalamin acetate | 22465-48-1 | 2A-9039004 |
| 5-Methyl-[1,4]diazepane | 22777-05-5 | 2A-9039068 |
| 2-Methyl-L-phenylalanine monohydrate | 23239-35-2 | 2A-9039216 |
| DL-Valine ethyl ester hydrochloride | 23358-42-1 | 2A-9039243 |
| L-Valyl-L-tyrosine | 24587-37-9 | 2A-9039517 |
| Chondroitin 4-sulfate | 24967-93-9 | 2A-9039596 |
| Poly-L-leucine | 25322-63-8 | 2A-9039706 |
| Browse all Nutritional Ingredients products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS