CAS Number6153-33-9
SynonymsMebhydroline 1,5-naphthalenedisulfonate salt; diazoline; Naphthalene-1,5-disulfonic acid - 5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (1:2); 1,5-Naphthalenedisulfonic acid - 5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (1:2); Mebhydrolin napadisylate; Mebhydroline Napadisylate
Molecular FormulaC48H48N4O6S2
Molecular Weight841.06
Purity98.00%
Density0.9799 (rough estimate)
Boiling Point457.3ºC at 760 mmHg
Melting Point280°C (rough estimate)
AppearanceWhite or almost white crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6153-33-9 |
| Catalog No. | 2A-9032532 |
| Chinese Name | 美海屈林萘二磺酸盐 |
| Synonyms | Mebhydroline 1,5-naphthalenedisulfonate salt; diazoline; Naphthalene-1,5-disulfonic acid - 5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (1:2); 1,5-Naphthalenedisulfonic acid - 5-benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (1:2); Mebhydrolin napadisylate; Mebhydroline Napadisylate |
| Molecular Formula | C48H48N4O6S2 |
| Molecular Weight | 841.06 |
| Purity | 98.00 |
| Density | 0.9799 (rough estimate) |
| Boiling Point | 457.3ºC at 760 mmHg |
| Melting Point | 280°C (rough estimate) |
| Appearance | White or almost white crystal |
| Storage Condition | room temperature, inert gas |
| Application | Mebhydrolin napadisylate is a specific histamine H1 receptor antagonist. |
| HTC | 2933990090 |
| MDL Number | C19H20N2·1/2C10H8O6S2 |
| SMILES | CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1.CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12 |
| InChI | InChI=1S/2C19H20N2.C10H8O6S2/c2*1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15;11-17(12,13)9-5-1-3-7-8(9)4-2-6-10(7)18(14,15)16/h2*2-10H,11-14H2,1H3;1-6H,(H,11,12,13)(H,14,15,16) |
| InChI Key | CJUOSBUQOWKEKJ-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/32532_1_6153_33_9.pdf |
| Bioactivity | Mebhydrolin napadisylate is a specific histamine H1 receptor antagonist. Related Catalog Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Target Histamine H1-receptor[1] In Vitro Mebhydrolin is a specific histamine H1-receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine[1]. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study[2]. References [1]. O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7. [2]. Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9. Chemical & Physical Properties Density 0.9799 (rough estimate) Boiling Point 457.3ºC at 760 mmHg Melting Point 280°C (rough estimate) Molecular Formula C48H48N4O6S2 Molecular Weight 841.048 Flash Point 230.4ºC Exact Mass 840.301514 PSA 141.84000 LogP 10.72560 Index of Refraction 1.8676 (estimate) InChIKey CJUOSBUQOWKEKJ-UHFFFAOYSA-N SMILES CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1.CN1CCc2c(c3ccccc3n2Cc2ccccc2)C1.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12 |
| Use of | Mebhydrolin napadisylate is a specific histamine H1 receptor antagonist. Properties Articles13 Name Mebhydrolin Napadisylate Synonym More Synonyms Mebhydrolin napadisylate Biological Activity Description Mebhydrolin napadisylate is a specific histamine H1 receptor antagonist. Related Catalog Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Histamine H1-receptor[1] In Vitro Mebhydrolin is a specific histamine H1-receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine[1]. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study[2]. References [1]. O'Neill PA, et al. Chlorpromazine-a specific effect on breathlessness? Br J Clin Pharmacol. 1985 Jun;19(6):793-7. [2]. Franks HM, et al. Interaction between ethanol and antihistamines: 3. Mebhydrolin. Med J Aust. 1981 Oct 31;2(9):477-9. Chemical & Physical Properties Molecular Formula C48H48N4O6S2 Exact Mass 840.301514 PSA 141.84000 LogP 10.72560 Index of Refraction 1.8676 (estimate) InChIKey CJUOSBUQOWKEKJ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 6-Nitrophthalide | 610-93-5 | 2A-9032519 |
| Ethyl potassium malonate | 6148-64-7 | 2A-9032521 |
| Sodium mesitylenesulfonate | 6148-75-0 | 2A-9032522 |
| Sodium diphenylamine-4-sulfonate | 6152-67-6 | 2A-9032528 |
| (Z)-3-Methylpent-2-en-4-yn-1-ol | 6153-05-5 | 2A-9032529 |
| Methyl orotate | 6153-44-2 | 2A-9032534 |
| Oxalic acid dihydrate | 6153-56-6 | 2A-0202062 |
| L-Rhamnose monohydrate | 6155-35-7 | 2A-9032538 |
| Manganese(II) acetate tetrahydrate | 6156-78-1 | 2A-9032540 |
| Vasicine | 6159-55-3 | 2A-9032542 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS