CAS Number6054-98-4
SynonymsAzodisal sodium; 3,3'-(E)-diazène-1,2-diylbis(6-hydroxybenzoate) de disodium; Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt; Benzoic acid, 3,3'-[(E)-1,2-diazenediyl]bis[6-hydroxy-, sodium salt (1:2); Olsalazine Sodium Salt; Dipentum; EINECS 227-975-7; Disodium 3,3'-[(E)-1,2-diazenediyl]bis(6-hydroxybenzoate); Olsalazine disodium; Dinatrium-3,3'-(E)-diazen-1,2-diylbis(6-hydroxybenzolcarboxylat); Disodium 3,3'-(E)-diazene-1,2-diylbis(6-hydroxybenzoate); MFCD00013300; Olsalazine (Disodium)
Molecular FormulaC14H8N2Na2O6
Molecular Weight346.20
Purity98.00%
Boiling Point557.9ºC at 760 mmHg
Melting Point240ºC
AppearanceYellow crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6054-98-4 |
| Catalog No. | 2A-9032442 |
| Chinese Name | 奥沙拉嗪钠 |
| Synonyms | Azodisal sodium; 3,3'-(E)-diazène-1,2-diylbis(6-hydroxybenzoate) de disodium; Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt; Benzoic acid, 3,3'-[(E)-1,2-diazenediyl]bis[6-hydroxy-, sodium salt (1:2); Olsalazine Sodium Salt; Dipentum; EINECS 227-975-7; Disodium 3,3'-[(E)-1,2-diazenediyl]bis(6-hydroxybenzoate); Olsalazine disodium; Dinatrium-3,3'-(E)-diazen-1,2-diylbis(6-hydroxybenzolcarboxylat); Disodium 3,3'-(E)-diazene-1,2-diylbis(6-hydroxybenzoate); MFCD00013300; Olsalazine (Disodium) |
| Molecular Formula | C14H8N2Na2O6 |
| Molecular Weight | 346.20 |
| Purity | 98.00 |
| Boiling Point | 557.9ºC at 760 mmHg |
| Melting Point | 240ºC |
| Appearance | Yellow crystalline powder |
| Water Solubility | Water solubility: soluble; insoluble: ether, ethan |
| Storage Condition | -20°C Freezer |
| Application | Olsalazine is an anti-inflammatory compound that acts on inflammatory bowel disease and ulcerative colitis. |
| HTC | 2928000090 |
| SMILES | [Na+].[Na+].N(\N=C2/C=C(C(=O)C=C/2)C(=O)[O-])c1cc(c(cc1)O)C(=O)[O-] |
| InChI | 1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,15,17H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-8-;; |
| InChI Key | QQWFSVYVHLECFP-XBPUGJBTSA-L |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/32442_1_6054_98_4.pdf |
| Use of | Properties Articles25 Name olsalazine sodium Synonym More Synonyms Olsalazine (Disodium) Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Nielsen, O.H., H.W. Verspaget, and J. Elmgreen, Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid. Aliment Pharmacol Ther, 1988. 2(3): p. 203-11. [2]. Gionchetti, P., et al., Scavenger effect of sulfasalazine, 5-aminosalicylic acid, and olsalazine on superoxide radical generation. Dig Dis Sci, 1991. 36(2): p. 174-8. [3]. Brown, W.A., et al., 5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer. Dig Dis Sci, 2000. 45(8): p. 1578-84. Chemical & Physical Properties Molecular Formula C14H8N2Na2O6 Exact Mass 346.017761 PSA 145.44000 LogP 0.24020 Safety Information HS Code 2928000090 |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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