| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5579-66-8 |
| Catalog No. | 2A-9031984 |
| Chinese Name | 十甘醇 |
| Synonyms | 3,6,9,12,15,18,21,24,27-Nonaoxanonacosane-1,29-diol; EINECS 226-962-3; Decaethylene Glycol |
| Molecular Formula | C20H42O11 |
| Molecular Weight | 458.54 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 539.5±45.0 °C at 760 mmHg |
| Melting Point | 28ºC |
| Appearance | solid |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | Decaethylene glycol is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules. |
| HTC | 2909499000 |
| PubChem ID | 329777555 |
| MDL Number | MFCD00698693 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | 1S/C20H42O11/c21-1-3-23-5-7-25-9-11-27-13-15-29-17-19-31-20-18-30-16-14-28-12-10-26-8-6-24-4-2-22/h21-22H,1-20H2 |
| InChI Key | DTPCFIHYWYONMD-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| MSDS | msds/31984_1_5579_66_8.pdf |
| Bioactivity | Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 539.5±45.0 °C at 760 mmHg Melting Point 28ºC Molecular Formula C20H42O11 Molecular Weight 458.541 Flash Point 280.1±28.7 °C Exact Mass 458.272705 PSA 123.53000 LogP -4.38 Vapour Pressure 0.0±3.3 mmHg at 25°C Index of Refraction 1.464 InChIKey DTPCFIHYWYONMD-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Use of | Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name decaethylene glycol Synonym More Synonyms Decaethylene glycol Biological Activity Description Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C20H42O11 Exact Mass 458.272705 PSA 123.53000 LogP -4.38 Index of Refraction 1.464 InChIKey DTPCFIHYWYONMD-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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