CAS Number2140-79-6
SynonymsUNII-02YX82IHZ5; 2'-O-Methyl adenosine; 2'-methyl-adenosine; 2'-O-methylAdo; 2′-O-Methyladenosine; (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol; 2'-methoxyadenosine; 2'-OMeAdenosine; MFCD00056002; 2'-O-Methyladenosine; 2'-O-Methyl-D-adenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Adenosine,2'-O-methyl
Molecular FormulaC11H15O4N5
Molecular Weight281.27
Purity98.00%
Density1.8±0.1 g/cm3
Boiling Point623.8±65.0 °C at 760 mmHg
Melting Point200-202ºC
Appearancewhite solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2140-79-6 |
| Catalog No. | 2A-9028040 |
| Chinese Name | 2'-O-甲基腺苷 |
| Synonyms | UNII-02YX82IHZ5; 2'-O-Methyl adenosine; 2'-methyl-adenosine; 2'-O-methylAdo; 2′-O-Methyladenosine; (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol; 2'-methoxyadenosine; 2'-OMeAdenosine; MFCD00056002; 2'-O-Methyladenosine; 2'-O-Methyl-D-adenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Adenosine,2'-O-methyl |
| Molecular Formula | C11H15O4N5 |
| Molecular Weight | 281.27 |
| Purity | 98.00 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 623.8±65.0 °C at 760 mmHg |
| Melting Point | 200-202ºC |
| Appearance | white solid |
| Water Solubility | Water solubility: soluble |
| Storage Condition | −20°C |
| Application | 2'-O-Methyladenosine is a methylated adenine residue that can be detected in the urine of normal people and adenosine deaminase (ADA). 2'-O-Methyladenosine has unique antihypertensive activity. |
| HTC | 2934999090 |
| PubChem ID | 3718406 |
| MDL Number | MFCD00056002 |
| SMILES | COC1C(O)C(CO)OC1n1cnc2c(N)ncnc21 |
| InChI | InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1 |
| InChI Key | FPUGCISOLXNPPC-IOSLPCCCSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/28040_1_2140_79_6.pdf |
| Bioactivity | 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others In Vivo 2'-O-Methyladenosine (100, 200 mg/kg, ip, single dose) exhibits unique hypotensive activities in rats[2]. Animal Model: Male spontaneously hypertensive rats (SHR; 16 weeks old)[2]. Dosage: 100, 200 mg/kg. Administration: IP, single dose. Result: Exhibited a significant hypotensive effect in decreasing blood pressure by about 40-50%. References [1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9. [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 623.8±65.0 °C at 760 mmHg Melting Point 200-202ºC Molecular Formula C11H15N5O4 Molecular Weight 281.268 Flash Point 331.0±34.3 °C Exact Mass 281.112396 PSA 128.54000 LogP -0.15 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.795 InChIKey FPUGCISOLXNPPC-IOSLPCCCSA-N SMILES COC1C(O)C(CO)OC1n1cnc2c(N)ncnc21 Storage condition −20°C |
| Use of | 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2]. Properties Articles15 Name cordysinin B Synonym More Synonyms 2'-O-Methyladenosine Biological Activity Description 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities [1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others References [1]. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9. [2]. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8. Chemical & Physical Properties Molecular Formula C11H15N5O4 Exact Mass 281.112396 PSA 128.54000 LogP -0.15 Index of Refraction 1.795 InChIKey FPUGCISOLXNPPC-IOSLPCCCSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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