CAS Number1758-80-1
SynonymsL-DAB HBR; MFCD07368664; L-2,4-Diaminobutyric acid hydrobromine; (2S)-2,4-Diaminobutanoic acid hydrobromide (1:1); Butanoic acid, 2,4-diamino-, (2S)-, hydrobromide (1:1); L-DABA; L-Dab.HBr; H-Dab.HBr
Molecular FormulaC4H10O2N2
Molecular Weight118.14
Purity98.00%
Density1.218 g/cm3
Boiling Point321ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1758-80-1 |
| Catalog No. | 2A-9027427 |
| Chinese Name | L-2,4-二氨基丁酸氢溴酸盐 |
| Synonyms | L-DAB HBR; MFCD07368664; L-2,4-Diaminobutyric acid hydrobromine; (2S)-2,4-Diaminobutanoic acid hydrobromide (1:1); Butanoic acid, 2,4-diamino-, (2S)-, hydrobromide (1:1); L-DABA; L-Dab.HBr; H-Dab.HBr |
| Molecular Formula | C4H10O2N2 |
| Molecular Weight | 118.14 |
| Purity | 98.00 |
| Density | 1.218 g/cm3 |
| Boiling Point | 321ºC at 760 mmHg |
| Storage Condition | 2-8°C, sealed, dry, protected from light |
| Application | L-DABA (L-2,4-Diaminobutyric acid) is a weak inhibitor of GABA transaminase, with an IC50 value greater than 500 μM. It has antitumor activity in vivo and in vitro. |
| HTC | 2922499990 |
| PubChem ID | 6142 |
| MDL Number | MFCD00082632 |
| SMILES | NCCC(N)C(=O)O |
| InChI | InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8) |
| InChI Key | OGNSCSPNOLGXSM-VKHMYHEASA-N |
| MSDS | msds/27427_1_1758_80_1.pdf |
| Use of | L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro. Properties Name L-2,4-diaminobutyric acid Synonym More Synonyms H-Dab.HBr Biological Activity Description L-DABA (L-2,4-Diaminobutyric acid) is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Research Areas >> Neurological Disease Natural Products >> Others Human Endogenous Metabolite In Vivo Treatment with L-DABA results in 43.4% reduction of tumor growth[1]. L-DABA is a more effective inhibitor of GABA transaminase in vivo than in vitro[2]. References [1]. Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68. [2]. Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8. [3]. Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4. Chemical & Physical Properties Molecular Formula C4H10N2O2 PSA 89.34000 LogP 1.10580 Index of Refraction 1.513 InChIKey OGNSCSPNOLGXSM-VKHMYHEASA-N SMILES NCCC(N)C(=O)O Safety Information Hazard Codes Xi HS Code 2922499990 Precursor & DownStream Precursor 0 DownStream 8 CAS#:7729-30-8 (2R)-2-Azetidin... CAS#:10270-94-7 H-Daba(Boc)-OH CAS#:34404-27-8 boc-l-dab(boc) CAS#:3350-20-7 N-α-t-Butoxycar... |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | P. Quarantine of entry animals, plants, and animal and plant products Q. Quarantine of exit animals, plants, and animal and plant products R. Hygiene supervision and inspection of imported food S. Hyg |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Related Products in Agrochemical Intermediates | ||
|---|---|---|
| 6-Fluoro-2,4-dihydroxyquinoline | 1677-37-8 | 2A-9027258 |
| 2,4-Dimethylcinnamic acid | 1685-80-9 | 2A-9027279 |
| 2,4-Dichloro-6-phenyl-1,3,5-triazine | 1700-02-3 | 2A-9027306 |
| Isobutyl 2,4-dichlorophenoxyacetate | 1713-15-1 | 2A-9027341 |
| 2,4,5-Triiodoimidazole | 1746-25-4 | 2A-9027408 |
| L-2,4-Diaminobutyric acid dihydrochloride | 1883-09-6 | 2A-9027632 |
| 2,4-Diaminoquinazoline | 1899-48-5 | 2A-9027659 |
| Paraquat dichloride | 1910-42-5 | 2A-9027671 |
| Dicamba | 1918-00-9 | 2A-9027685 |
| Octyl (2,4-dichlorophenoxy)acetate | 1928-44-5 | 2A-9027693 |
| Browse all Agrochemical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS