CAS Number1200-22-2
SynonymsThioctic acid; MFCD01631142; (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid; DL-Thioctic acid; (R)-(+)-1,2-Dithiolane-3-pentanoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid; (R)-1,2-Dithiolane-3-valeric Acid; (R)-Alpha-Lipoic Acid; 1,2-Dithiolane-3-pentanoic acid; 5-[(3R)-dithiolan-3-yl]pentanoic acid; (R)-(+)-α-Lipoic acid; (R)-6,8-Thioctic acid; (R)-Thioctic Acid; (±)-1,2-Dithiolane-3-valeric acid; (R)-6,8-Dithiooctanoic acid; 6,8-Dihydrothioctic acid; lipoic acid; UNII:73Y7P0K73Y; (R)-α-Lipoic Acid
Molecular FormulaC8H14O2S2
Molecular Weight206.33
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point362.5±11.0 °C at 760 mmHg
Melting Point46-49ºC
AppearanceYellow crystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1200-22-2 |
| Catalog No. | 2A-9026474 |
| Chinese Name | (R)-(+)-1,2-二硫戊环基-3-戊酸 |
| Synonyms | Thioctic acid; MFCD01631142; (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid; DL-Thioctic acid; (R)-(+)-1,2-Dithiolane-3-pentanoic acid; 5-(1,2-Dithiolan-3-yl)pentanoic acid; (R)-1,2-Dithiolane-3-valeric Acid; (R)-Alpha-Lipoic Acid; 1,2-Dithiolane-3-pentanoic acid; 5-[(3R)-dithiolan-3-yl]pentanoic acid; (R)-(+)-α-Lipoic acid; (R)-6,8-Thioctic acid; (R)-Thioctic Acid; (±)-1,2-Dithiolane-3-valeric acid; (R)-6,8-Dithiooctanoic acid; 6,8-Dihydrothioctic acid; lipoic acid; UNII:73Y7P0K73Y; (R)-α-Lipoic Acid |
| Molecular Formula | C8H14O2S2 |
| Molecular Weight | 206.33 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 362.5±11.0 °C at 760 mmHg |
| Melting Point | 46-49ºC |
| Appearance | Yellow crystalline solid |
| Water Solubility | Water solubility: insoluble |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant and an important cofactor for mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more potent than racemic Lipoic acid. |
| HTC | 2934999090 |
| PubChem ID | 329747929 |
| SMILES | O=C(O)CCCCC1CCSS1 |
| InChI | InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1 |
| InChI Key | AGBQKNBQESQNJD-SSDOTTSWSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology Target Human Endogenous Metabolite In Vitro Lipoic acid ((R)-(+)-α-Lipoic acid) is the form biosynthesized in humans which is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α-Lipoic acid) constitute the racemic mixture Lipoic acid. Only the Lipoic acid ((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) has been suggested to be nutritionally and therapeutically preferred form as antioxidant[1]. References [1]. Nasole E, et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. J Enzyme Inhib Med Chem. 2014 Apr;29(2):297-302. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 362.5±11.0 °C at 760 mmHg Melting Point 46-49ºC Molecular Formula C8H14O2S2 Molecular Weight 206.326 Flash Point 173.0±19.3 °C Exact Mass 206.043518 PSA 87.90000 LogP 2.16 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.562 InChIKey AGBQKNBQESQNJD-SSDOTTSWSA-N SMILES O=C(O)CCCCC1CCSS1 Storage condition -20°C Freezer |
| Use of | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Properties Articles33 Name (R)-lipoic acid Synonym More Synonyms lipoic acid Biological Activity Description Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology Human Endogenous Metabolite In Vitro Lipoic acid ((R)-(+)-α-Lipoic acid) is the form biosynthesized in humans which is essential for aerobic metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) is the nutritionally and therapeutically preferred form due to its "vitamin-like" role in metabolism. Lipoic acid ((R)-(+)-α-Lipoic acid) and S-(-)-α-Lipoic acid) constitute the racemic mixture Lipoic acid. Only the Lipoic acid ((R)-(+)-α-Lipoic acid) exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Lipoic acid ((R)-(+)-α-Lipoic acid) has been suggested to be nutritionally and therapeutically preferred form as antioxidant[1]. References [1]. Nasole E, et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. J Enzyme Inhib Med Chem. 2014 Apr;29(2):297-302. Chemical & Physical Properties Molecular Formula C8H14O2S2 Exact Mass 206.043518 PSA 87.90000 Index of Refraction 1.562 InChIKey AGBQKNBQESQNJD-SSDOTTSWSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Nutritional Ingredients | ||
|---|---|---|
| N-Acetyl-3,5-diiodo-L-tyrosine | 1027-28-7 | 2A-9025961 |
| DL-Ornithine hydrochloride | 1069-31-4 | 2A-9026004 |
| L-Glutamic acid gamma-ethyl ester | 1119-33-1 | 2A-9026175 |
| N-p-Tosyl-L-arginine | 1159-15-5 | 2A-9026354 |
| N-Carbamyl-L-glutamic acid | 1188-38-1 | 2A-9026402 |
| Tocopherol | 1406-18-4 | 2A-9026767 |
| D-Erythro-sphingosylphosphorylcholine | 1670-26-4 | 2A-9027239 |
| L-Leucine benzyl ester p-toluenesulfonate salt | 1738-77-8 | 2A-9027396 |
| N-4-Tosyl-L-arginine methyl ester hydrochloride | 1784-03-8 | 2A-9027474 |
| Bromazepam | 1812-30-2 | 2A-9027512 |
| Browse all Nutritional Ingredients products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS