
CAS Number1119-34-2
Synonyms(+)-L-arginine hydrochloride; (2S)-2-amino-5-carbamimidamidopentanoic acid hydrochloride; levargin; L-Arginine HCl; L-(+)-Arginine monohydrochloride; L-Arginine hydrochloride; L-ARG HCL; (S)-2-Amino-5-guanidinopentanoic acid hydrochloride; (S)-(+)-Arginine hydrochloride,L-Arginine hydrochloride; L-Arginine hydrochloride (1:1); (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride; 2-Amino-5-guanidinovalericacidmonohydrochloride; anhydrous L-arginine monohydrochloride; L-Arginine HCl (L-Arg); Arginine hydrochloride; L-Arginine.HCl; Arginine Muriate; S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride; (S)-arginine hydrochloride; L(+)-Arginine hydrochloride; ARG,HCL; (2S)-2-Amino-5-carbamimidamidopentansäurehydrochlorid; L-Arginine, hydrochloride (
Molecular FormulaC6H15ClN4O2
Molecular Weight210.66
Purity98.00%
Density1.42
Boiling Point409.1ºC at 760 mmHg
Melting Point226-230 °C(lit.)
AppearanceWhite crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1119-34-2 |
| Catalog No. | 2A-0200190 |
| Chinese Name | L-精氨酸盐酸盐 |
| Synonyms | (+)-L-arginine hydrochloride; (2S)-2-amino-5-carbamimidamidopentanoic acid hydrochloride; levargin; L-Arginine HCl; L-(+)-Arginine monohydrochloride; L-Arginine hydrochloride; L-ARG HCL; (S)-2-Amino-5-guanidinopentanoic acid hydrochloride; (S)-(+)-Arginine hydrochloride,L-Arginine hydrochloride; L-Arginine hydrochloride (1:1); (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride; 2-Amino-5-guanidinovalericacidmonohydrochloride; anhydrous L-arginine monohydrochloride; L-Arginine HCl (L-Arg); Arginine hydrochloride; L-Arginine.HCl; Arginine Muriate; S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride; (S)-arginine hydrochloride; L(+)-Arginine hydrochloride; ARG,HCL; (2S)-2-Amino-5-carbamimidamidopentansäurehydrochlorid; L-Arginine, hydrochloride ( |
| Molecular Formula | C6H15ClN4O2 |
| Molecular Weight | 210.66 |
| Purity | 98.00 |
| Density | 1.42 |
| Boiling Point | 409.1ºC at 760 mmHg |
| Melting Point | 226-230 °C(lit.) |
| Appearance | White crystalline powder |
| Storage Condition | Stable under normal temperature and pressure, avoi |
| Application | L-Arginine hydrochloride is a nitrogen donor for the synthesis of nitric oxide and a vasodilator. |
| HTC | 2922499990 |
| PubChem ID | 3132037 |
| SMILES | [Cl-].N[C@@H](CCCN=C(N)N)C(O)=O.[H+] |
| InChI | InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1 |
| InChI Key | InChIKey=KWTQSFXGGICVPE-WCCKRBBISA-N |
| Hazard Symbols | transportation |
| Bioactivity | L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.Target: OthersArginine is an α-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Others Natural Products >> Others References [1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. Chemical & Physical Properties Density 1.42 Boiling Point 409.1ºC at 760 mmHg Melting Point 226-230 °C(lit.) Molecular Formula C6H15ClN4O2 Molecular Weight 210.662 Flash Point 201.2ºC Exact Mass 210.088348 PSA 125.22000 LogP 1.35480 |
| Use of | Properties Articles19 Name 2-Amino-5-guanidinovaleric acid monohydrochloride Synonym More Synonyms L-Arginine hydrochloride Biological Activity Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Others Natural Products >> Others References [1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. Chemical & Physical Properties Exact Mass 210.088348 PSA 125.22000 LogP 1.35480 |
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