CAS Number367-93-1
SynonymsMFCD00063273; UNII-X73VV2246B; (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-propan-2-ylsulfanyloxane-3,4,5-triol; Isopropyl-β-D-thiogalactoside; Isopropyl β-D-thiogalactoside; EINECS 206-703-0; Isopropyl β-D-thiogalactoside (IPTG); IPTG
Molecular FormulaC9H18O5S
Molecular Weight238.30
Purity≥99 (TLC)%
Density1.4±0.1 g/cm3
Boiling Point438.4±45.0 °C at 760 mmHg
Melting Point105 °C ((221 °F))
Appearancepowder
EINECS206-703-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 367-93-1 |
| Catalog No. | 2A-9021547 |
| Chinese Name | 异丙基-β-D-硫代半乳糖苷(IPTG) |
| Synonyms | MFCD00063273; UNII-X73VV2246B; (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-propan-2-ylsulfanyloxane-3,4,5-triol; Isopropyl-β-D-thiogalactoside; Isopropyl β-D-thiogalactoside; EINECS 206-703-0; Isopropyl β-D-thiogalactoside (IPTG); IPTG |
| Molecular Formula | C9H18O5S |
| Molecular Weight | 238.30 |
| Purity | ≥99 (TLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 438.4±45.0 °C at 760 mmHg |
| Melting Point | 105 °C ((221 °F)) |
| Appearance | powder |
| Water Solubility | soluble |
| Storage Condition | Should be stored at -20℃. |
| Application | IPTG is an allolactose mimic that can cause the transcription process of the lactose operon, and therefore can induce the expression of proteins corresponding to genes downstream of the lactose operon |
| EINECS | 206-703-0 |
| HTC | 2932999099 |
| PubChem ID | 24896093 |
| MDL Number | MFCD00063273 |
| SMILES | CC(C)S[C@@H]1OC(CO)[C@H](O)C(O)[C@H]1O |
| InChI | 1S/C9H18O5S/c1-4(2)15-9-8(13)7(12)6(11)5(3-10)14-9/h4-13H,3H2,1-2H3/t5-,6+,7+,8-,9+/m1/s1 |
| InChI Key | BPHPUYQFMNQIOC-NXRLNHOXSA-N |
| Beilstein/REAXYS | 4631 |
| NACRES Code | NA.31 |
| UNSPSC | 12352201 |
| Hazard Symbols | Transport |
| MSDS | msds/21547_1_367_93_1.pdf |
| Bioactivity | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others In Vitro IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1]. References [1]. Isopropyl β-D-1-thiogalactopyranoside Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 438.4±45.0 °C at 760 mmHg Melting Point 105 °C Molecular Formula C9H18O5S Molecular Weight 238.301 Flash Point 218.9±28.7 °C Exact Mass 238.087494 PSA 115.45000 LogP -1.01 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.578 InChIKey BPHPUYQFMNQIOC-NXRLNHOXSA-N SMILES CC(C)SC1OC(CO)C(O)C(O)C1O Water Solubility soluble |
| Use of | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Properties Articles715 Name isopropyl β-D-thiogalactopyranoside Synonym More Synonyms Isopropyl-beta-D-thiogalactopyranoside Biological Activity Description IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others In Vitro IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1]. References [1]. Isopropyl β-D-1-thiogalactopyranoside Chemical & Physical Properties Molecular Formula C9H18O5S Exact Mass 238.087494 PSA 115.45000 LogP -1.01 Index of Refraction 1.578 InChIKey BPHPUYQFMNQIOC-NXRLNHOXSA-N SMILES CC(C)SC1OC(CO)C(O)C(O)C1O Water Solubility soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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