CAS Number138-60-3
Synonymschelidamic acid; 4-Hydroxypyridine-2,6-dicarboxylic Acid Monohydrate; 4-oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid; MFCD00066478; 4-Hydroxy-2,6-pyridinedicarboxylic acid; 4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid; 4-PYRIDONE-2,6-DICARBOXYLIC ACID; 1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid; .HELIDAMIC AICD; CHELIDAMIC ACID HYDRATE; Chelidamaic acid; Chelidamic Acid Monohydrate; Chelidamic aicd; Ammox-chelidonic acid; 4-Hydroxypyridine-2,6-dicarboxylic acid; chelidamic acid approx.; EINECS 205-335-8; 4-hydroxyl-pyridine-2,6-dicarboxylic acid
Molecular FormulaC7H5NO5
Molecular Weight183.12
Purity98.00%
Density1.7±0.1 g/cm3
Boiling Point428.3±45.0 °C at 760 mmHg
Melting Point265-270 °C
Appearancepowder
EINECS205-335-8
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 138-60-3 |
| Catalog No. | 2A-9020814 |
| Chinese Name | 白屈氨酸 |
| Synonyms | chelidamic acid; 4-Hydroxypyridine-2,6-dicarboxylic Acid Monohydrate; 4-oxo-1,4-dihydro-2,6-pyridinedicarboxylic acid; MFCD00066478; 4-Hydroxy-2,6-pyridinedicarboxylic acid; 4-oxo-1,4-dihydropyridine-2,6-dicarboxylic acid; 4-PYRIDONE-2,6-DICARBOXYLIC ACID; 1,4-dihydro-4-oxo-2,6-pyridinedicarboxylic acid; .HELIDAMIC AICD; CHELIDAMIC ACID HYDRATE; Chelidamaic acid; Chelidamic Acid Monohydrate; Chelidamic aicd; Ammox-chelidonic acid; 4-Hydroxypyridine-2,6-dicarboxylic acid; chelidamic acid approx.; EINECS 205-335-8; 4-hydroxyl-pyridine-2,6-dicarboxylic acid |
| Molecular Formula | C7H5NO5 |
| Molecular Weight | 183.12 |
| Purity | 98.00 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 428.3±45.0 °C at 760 mmHg |
| Melting Point | 265-270 °C |
| Appearance | powder |
| Storage Condition | Room Temperature |
| Application | Chelidamic acid is a heterocyclic organic acid containing a pyran skeleton and has good coordination ability with metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate dec |
| EINECS | 205-335-8 |
| HTC | 2933399090 |
| PubChem ID | 329768367 |
| MDL Number | MFCD00066478 |
| SMILES | Oc1cc(nc(c1)C(O)=O)C(O)=O |
| InChI | 1S/C7H5NO5/c9-3-1-4(6(10)11)8-5(2-3)7(12)13/h1-2H,(H,8,9)(H,10,11)(H,12,13) |
| InChI Key | XTLJJHGQACAZMS-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| MSDS | msds/20814_1_138_60_3.pdf |
| Bioactivity | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Target Ki: 33 μM (Glutamate decarboxylase)[3]. In Vitro Chelidamic acid is a heterocyclic organic acid with a pyran skeleton[1]. Chelidamic acid has good coordination ability with noble metal ions[2]. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM[3]. References [1]. Searcey M, et al. Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anticancer Drug Des. 13(8):837-55. [2]. Espinet P, et al. Mesogenic palladium complexes with pincer ligands derived from dipicolinic acid. Inorg Chem. 2000 Aug, 7;39(16):3645-51. [3]. Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 428.3±45.0 °C at 760 mmHg Melting Point 267 °C (dec.)(lit.) Molecular Formula C7H5NO5 Molecular Weight 183.118 Flash Point 212.8±28.7 °C Exact Mass 183.016769 PSA 107.46000 LogP -1.43 Vapour Pressure 0.0±2.2 mmHg at 25°C Index of Refraction 1.635 InChIKey XTLJJHGQACAZMS-UHFFFAOYSA-N SMILES O=C(O)c1cc(=O)cc(C(=O)O)[nH]1 |
| Use of | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. Properties Name Chelidamic acid Synonym More Synonyms chelidamic acid Biological Activity Description Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Ki: 33 μM (Glutamate decarboxylase)[3]. In Vitro Chelidamic acid is a heterocyclic organic acid with a pyran skeleton[1]. Chelidamic acid has good coordination ability with noble metal ions[2]. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM[3]. References [1]. Searcey M, et al. Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anticancer Drug Des. 13(8):837-55. [2]. Espinet P, et al. Mesogenic palladium complexes with pincer ligands derived from dipicolinic acid. Inorg Chem. 2000 Aug, 7;39(16):3645-51. [3]. Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50. Chemical & Physical Properties Molecular Formula C7H5NO5 Exact Mass 183.016769 PSA 107.46000 LogP -1.43 Index of Refraction 1.635 InChIKey XTLJJHGQACAZMS-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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