CAS Number138-37-4
Synonymsα-Amino-p-toluenesulfonamide hydrochloride; 4-(Aminomethyl)benzenesulfonamide hydrochloride; p-Toluenesulfonamide, α-amino-, hydrochloride; 4-(Aminomethyl)benzenesulfonamide hydrochloride (1:1); HoMosulfaMine Hydrochloride; 4-(aminomethyl)benzenesulfonamide,hydrochloride; MFCD00013005; Mafenide HCl; p-Toluenesulfonamide, α-amino-, monohydrochloride; 4-Aminomethylbenzenesulfonamide hydrochloride; a-amino-p-toluenesulfonamide hydrochloride; 4-Homosulfanilamide,Mafenide,Marfanil; EINECS 205-325-3; Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1); Mafenide Hydrochloride; Benzenesulfonamide, 4- (aminomethyl)-, monohydrochloride; Mafenide (hydrochloride)
Molecular FormulaC7H11ClN2O2S
Molecular Weight222.69
Purity≥95%
Boiling Point382ºC at 760mmHg
Melting Point261-263 °C(lit.)
AppearanceSolid;White to Almost white powder to crystal
EINECS205-325-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 138-37-4 |
| Catalog No. | 2A-9020807 |
| Chinese Name | 盐酸磺胺米隆 |
| Synonyms | α-Amino-p-toluenesulfonamide hydrochloride; 4-(Aminomethyl)benzenesulfonamide hydrochloride; p-Toluenesulfonamide, α-amino-, hydrochloride; 4-(Aminomethyl)benzenesulfonamide hydrochloride (1:1); HoMosulfaMine Hydrochloride; 4-(aminomethyl)benzenesulfonamide,hydrochloride; MFCD00013005; Mafenide HCl; p-Toluenesulfonamide, α-amino-, monohydrochloride; 4-Aminomethylbenzenesulfonamide hydrochloride; a-amino-p-toluenesulfonamide hydrochloride; 4-Homosulfanilamide,Mafenide,Marfanil; EINECS 205-325-3; Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1); Mafenide Hydrochloride; Benzenesulfonamide, 4- (aminomethyl)-, monohydrochloride; Mafenide (hydrochloride) |
| Molecular Formula | C7H11ClN2O2S |
| Molecular Weight | 222.69 |
| Purity | ≥95 |
| Boiling Point | 382ºC at 760mmHg |
| Melting Point | 261-263 °C(lit.) |
| Appearance | Solid;White to Almost white powder to crystal |
| Storage Condition | Room temperature, dry |
| Application | Mafenide hydrochloride is a sulfonamide antibiotic compound. |
| EINECS | 205-325-3 |
| HTC | 2935009090 |
| PubChem ID | 329770769 |
| MDL Number | MFCD00013005 |
| SMILES | Cl.NCc1ccc(cc1)S(N)(=O)=O |
| InChI | 1S/C7H10N2O2S.ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11;/h1-4H,5,8H2,(H2,9,10,11);1H |
| InChI Key | SIACJRVYIPXFKS-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/20807_1_138_37_4.pdf |
| Bioactivity | Mafenide hydrochloride is a sulfonamide-type medication used as an antibiotic.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Boiling Point 382ºC at 760mmHg Melting Point 261-263 °C(lit.) Molecular Formula C7H11ClN2O2S Molecular Weight 222.692 Flash Point 184.8ºC Exact Mass 222.022980 PSA 94.56000 LogP 3.07610 |
| Use of | Mafenide hydrochloride is a sulfonamide-type medication used as an antibiotic.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Properties Name Mafenide hydrochloride Synonym More Synonyms Mafenide hydrochloride Biological Activity Description Mafenide hydrochloride is a sulfonamide-type medication used as an antibiotic.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Exact Mass 222.022980 PSA 94.56000 LogP 3.07610 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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| Butyl lactate | 138-22-7 | 2A-9020804 |
| Phenyltrimethylammonium chloride | 138-24-9 | 2A-9020805 |
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