| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1844849-10-0 |
| Catalog No. | 2A-2194410 |
| Chinese Name | PF-06821497 |
| Molecular Formula | C22H24O5N2Cl2 |
| Molecular Weight | 467.35 |
| Application | PF-06821497 (compound 23a) is a potent, selective, orally available EZH2 (Enhancer of Zeste Homolog 2) inhibitor with a Ki value of <0.1 nM for Y641N EZH2. Has good anti-tumor activity. |
| PubChem ID | 312047804 |
| MDL Number | MFCD32062653 |
| InChI | InChI=1S/C22H24Cl2N2O5/c1-11-6-17(29-2)15(21(27)25-11)8-26-5-4-13-16(23)7-14(19(24)18(13)22(26)28)20(30-3)12-9-31-10-12/h6-7,12,20H,4-5,8-10H2,1-3H3,(H,25,27)/t20-/m1/s1 |
| InChI Key | RXCVUHMIWHRLDF-HXUWFJFHSA-N |
| MSDS | msds/196035_1_1844849_10_0.pdf |
| Transport Info | Product name: PF-06821497 |
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