
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 374620-70-9 |
| Catalog No. | 2A-2194407 |
| Chinese Name | NBI 31772 |
| Synonyms | 3-Isoquinolinecarboxylic acid,1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy |
| Molecular Formula | C17H11NO7 |
| Molecular Weight | 341.27200 |
| Storage Condition | -20°C |
| Application | NBI-31772 is a potent non-selective inhibitor of IGFBP with a Ki value of 47 nM. NBI-31772 has the potential to study IGF-responsive diseases [1]. |
| PubChem ID | 14900330 |
| InChI | InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25) |
| InChI Key | ZCMFEWUYBFMLIN-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | NBI-31772 is the potent and nonselective inhibitor of IGFBP with a Ki value of 47 nM. NBI-31772 has the potential for the research of IGF-responsive diseases[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R References [1]. Khawaja XZ. Development of a scintillation proximity assay for human insulin-like growth factor-binding protein 4 compatible with inhibitor high-throughput screening. Anal Biochem. 2007;366(1):80-86. Chemical & Physical Properties Molecular Formula C17H11NO7 Molecular Weight 341.27200 Exact Mass 341.05400 PSA 147.92000 LogP 0.85900 Storage condition -20°C |
| Use of | NBI-31772 is the potent and nonselective inhibitor of IGFBP with a Ki value of 47 nM. NBI-31772 has the potential for the research of IGF-responsive diseases[1]. Properties Name 1-[(3,4-dioxocyclohexa-1,5-dien-1-yl)-hydroxymethylidene]-6,7-dihydroxy-2H-isoquinoline-3-carboxylic acid Synonym More Synonyms NBI 31772 Biological Activity Description NBI-31772 is the potent and nonselective inhibitor of IGFBP with a Ki value of 47 nM. NBI-31772 has the potential for the research of IGF-responsive diseases[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R References Chemical & Physical Properties Molecular Formula C17H11NO7 Exact Mass 341.05400 PSA 147.92000 LogP 0.85900 |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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