| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1258984-36-9 |
| Catalog No. | 2A-3186577 |
| Chinese Name | Nusinersen |
| Synonyms | Nusinersen |
| Molecular Formula | C234H340N61O128P17S17 |
| Molecular Weight | 7127.194237 |
| Storage Condition | -20°C |
| Application | Nusinersen is an antisense oligonucleotide drug that can modify the pre-messenger RNA splicing of the SMN2 gene, thereby promoting the production of full-length SMN protein [1]. |
| SMILES | COCCOC1C(OP(O)(=S)OCC2OC(n3cnc4c(N)ncnc43)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(N)nc3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(=O)[nH]c3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(=O)[nH]c3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(=O)[nH]c3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(N)nc3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cnc4c(N)ncnc43)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(=O)[nH]c3=O)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cnc4c(N)ncnc43)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cnc4c(N)ncnc43)C(OCCOC)C2OP(O)(=S)OCC2OC(n3cc(C)c(=O)[nH]c3=O)C(OCCOC) |
| InChI Key | WWFDJIVIDXJAQR-FFWSQMGZSA-N |
| Transport Info | Product name: Oligonucleotide |
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