CAS Number58473-74-8
SynonymsMFCD00075351; cinromide; trans 3-bromo-N-ethylcinnamamide; Cinromide (usan/inn); m-Bromo-N-ethylcinnamamide; trans-3-Brom-N-ethylzimtsaeureamid; (e)-3-(3-bromophenyl)-n-ethyl-2-propenamide
Molecular FormulaC11H12O1N1Br1
Molecular Weight254.13
Density1.369g/cm3
Boiling Point417.5ºC at 760mmHg
Melting Point89-91ºC(lit.)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 58473-74-8 |
| Catalog No. | 2A-2178718 |
| Chinese Name | 反式-3-溴-N-乙基肉桂酰胺 |
| Synonyms | MFCD00075351; cinromide; trans 3-bromo-N-ethylcinnamamide; Cinromide (usan/inn); m-Bromo-N-ethylcinnamamide; trans-3-Brom-N-ethylzimtsaeureamid; (e)-3-(3-bromophenyl)-n-ethyl-2-propenamide |
| Molecular Formula | C11H12O1N1Br1 |
| Molecular Weight | 254.13 |
| Density | 1.369g/cm3 |
| Boiling Point | 417.5ºC at 760mmHg |
| Melting Point | 89-91ºC(lit.) |
| Storage Condition | 2-8℃ |
| Application | Cinromide is a broad-spectrum anticonvulsant. |
| HTC | 2924299090 |
| MDL Number | MFCD00075351 |
| SMILES | CCNC(=O)C=Cc1cccc(Br)c1 |
| InChI | InChI=1S/C11H12BrNO/c1-2-13-11(14)7-6-9-4-3-5-10(12)8-9/h3-8H,2H2,1H3,(H,13,14)/b7-6+ |
| InChI Key | LDCXGZCEMNMWIL-VOTSOKGWSA-N |
| MSDS | msds/179414_1_58473_74_8.pdf |
| Use of | Cinromide is a broad-spectrum anticonvulsant agent. Properties Articles17 Name trans-3-bromo-n-ethylcinnamamide Synonym More Synonyms Cinromide Biological Activity Description Cinromide is a broad-spectrum anticonvulsant agent. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease In Vitro Cinromide (10-100 μM) inhibits 5-HT-induced contractions in rat fundus strips by 46%. Cinromide (100 μM) inhibits monoamine oxidase prepared from both liver and brain of rats[1]. References [1]. Soroko FE, et al. Cinromide (3-bromo-N-ethylcinnanamide), novel anticonvulsant agent. J Pharm Pharmacol. 1981 Nov;33(11):741-3. [2]. Fromm GH, et al. Effect of cinromide on inhibitory and excitatory mechanisms. Epilepsia. 1983 Aug;24(4):394-400. Chemical & Physical Properties Molecular Formula C11H12BrNO Exact Mass 253.01000 PSA 29.10000 LogP 2.98930 Index of Refraction 1.591 InChIKey LDCXGZCEMNMWIL-VOTSOKGWSA-N Storage condition 2-8℃ Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 2-Propenamide, 3-(3-bromophenyl)-N-ethyl-, (E)- CAS REGISTRY NUMBER : 58473-74-8 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C11-H12-Br-N-O MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : Safety Information Signal Word Warning Hazard Statements H315-H319-H335 Precautionary Statements P261-P305 + P351 + P338 RIDADR NONH for all modes of transport RTECS UC6314000 HS Code 2924299090 Synthetic Route Total: 1 Page Ethylamine CAS#:75-04-7 (E)-ethyl 3-(3-... CAS#:59114-88-4 CAS#:58473-74-8 Literature: Burroughs Wellcome Co. Patent: US4041071 A1, 1977 ; Precursor & DownStream Precursor 2 CAS#:75-04-7 Ethylamine CAS#:59114-88-4 (E)-ethyl 3-(3-... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| ETHYL 3-AMINO-4-HYDROXYBENZOATE | 13052-92-1 | 2A-4178711 |
| 3-(5-mercapto-1,3,4-oxadiazol-2-yl)benzonitrile | 203268-77-3 | 2A-4178712 |
| OXANTEL PAMOATE | 68813-55-8 | 2A-2178715 |
| 2-(4-CHLOROPHENYL)INDANE-1,3-DIONE | 1146-99-2 | 2A-2178716 |
| PYRANTEL TARTRATE SALT | 33401-94-4 | 2A-2178717 |
| 3-HYDROXY-P-BUTYROPHENETIDINE | 1083-57-4 | 2A-2178719 |
| CINCHOPHEN | 132-60-5 | 2A-2178720 |
| 2-PHENYL-1,3-INDANDIONE | 83-12-5 | 2A-2178721 |
| SULOCTIDIL | 54767-75-8 | 2A-2178722 |
| MOLINDONE HYDROCHLORIDE | 15622-65-8 | 2A-2178723 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS