OXANTEL PAMOATE structure, CAS 68813-55-8

OXANTEL PAMOATE

CAS Number68813-55-8

SynonymsTelopar (TN); EINECS 272-332-6; UNII-UPY1D732T0; Telopar; Oxantel embonate; Oxantel pamoate (USAN); OXANTEL PAMOATE; Oxantel (pamoate)

Molecular FormulaC36H32N2O7

Molecular Weight604.66

Purity

Density1.09 g/cm3

Boiling Point383.1ºC at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-2178715 Purity:
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Quality Control of [ 68813-55-8 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number68813-55-8
Catalog No.2A-2178715
Chinese Name酚嘧啶 扑蛲灵
SynonymsTelopar (TN); EINECS 272-332-6; UNII-UPY1D732T0; Telopar; Oxantel embonate; Oxantel pamoate (USAN); OXANTEL PAMOATE; Oxantel (pamoate)
Molecular FormulaC36H32N2O7
Molecular Weight604.66
Density1.09 g/cm3
Boiling Point383.1ºC at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationOxantel pamoate is a widely used repellent that is effective against Trichuris muris and hookworms.
MDL NumberC36H32N2O7
SMILESCN1CCCN=C1\C=C\c2cccc(O)c2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O
InChIInChI=1S/C23H16O6.C13H16N2O/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-7,10,16H,3,8-9H2,1H3/b;7-6+
InChI KeyInChIKey=CCOAINFUFGBHBA-UETGHTDLSA-N
Hazard Symbolstransportation
MSDSmsds/179411_1_68813_55_8.pdf
BioactivityOxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Target Antiparasitic[1] In Vivo The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1]. References [1]. Keiser J, et al. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013;7(3):e2119. Chemical & Physical Properties Density 1.09 g/cm3 Boiling Point 383.1ºC at 760 mmHg Molecular Formula C36H32N2O7 Molecular Weight 604.65 Flash Point 185.5ºC PSA 186.72000 LogP 7.41720 Storage condition -20℃
Use ofOxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. Properties Name 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol Synonym More Synonyms Oxantel (pamoate) Biological Activity Description Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Antiparasitic[1] References [1]. Keiser J, et al. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013;7(3):e2119. Chemical & Physical Properties Molecular Formula C36H32N2O7 PSA 186.72000 LogP 7.41720 Storage condition -20℃
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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