| Chemical & Physical Properties | |
|---|---|
| CAS Number | 83-12-5 |
| Catalog No. | 2A-2178721 |
| Chinese Name | 苯茚二酮 |
| Synonyms | 2-PHENYL-1,3-INDANDIONE; 2-phenylindene-1,3-dione; EINECS 201-454-4; MFCD00003782 |
| Molecular Formula | C15H10O2 |
| Molecular Weight | 222.24 |
| Density | 1.343g/cm3 |
| Boiling Point | 243.3 °C (0.3 mmHg) |
| Melting Point | 144-148 °C(lit.) |
| Storage Condition | Protect from light and keep airtight. |
| Packaging | III |
| Application | Phenindione is an anticoagulant and acts as a vitamin K antagonist. |
| HTC | 2914399090 |
| MDL Number | MFCD00995893 |
| SMILES | O=C1c2ccccc2C(=O)C1c1ccccc1 |
| InChI | InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H |
| InChI Key | NFBAXHOPROOJAW-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/179418_1_83_12_5.pdf |
| Bioactivity | Phenindione is an anticoagulant which functions as a Vitamin K antagonist.Target: OthersPhenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Naisbitt, D.J., et al., Characterization of the T-cell response in a patient with phenindione hypersensitivity. Journal of Pharmacology and Experimental Therapeutics, 2005. 313(3): p. 1058-1065. Chemical & Physical Properties Density 1.343g/cm3 Boiling Point 243.3 °C (0.3 mmHg) Melting Point 144-148 °C(lit.) Molecular Formula C15H10O2 Molecular Weight 222.23900 Flash Point 208 °C Exact Mass 222.06800 PSA 34.14000 LogP 2.84940 Index of Refraction 1.703 InChIKey NFBAXHOPROOJAW-UHFFFAOYSA-N SMILES O=C1c2ccccc2C(=O)C1c1ccccc1 Storage condition 2-8°C |
| Use of | Phenindione is an anticoagulant which functions as a Vitamin K antagonist.Target: OthersPhenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1]. Properties Articles27 Name phenindione Synonym More Synonyms Phenindione Biological Activity Description Phenindione is an anticoagulant which functions as a Vitamin K antagonist.Target: OthersPhenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Naisbitt, D.J., et al., Characterization of the T-cell response in a patient with phenindione hypersensitivity. Journal of Pharmacology and Experimental Therapeutics, 2005. 313(3): p. 1058-1065. Chemical & Physical Properties Molecular Formula C15H10O2 Exact Mass 222.06800 PSA 34.14000 LogP 2.84940 Index of Refraction 1.703 InChIKey NFBAXHOPROOJAW-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (Phenindione) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Phenindione) International air transport hazard regulations: Toxic solid, organic, n.o.s. (Phenindione) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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