CAS Number94-07-5
Synonymssynefrin; simpatol; EINECS 202-300-9; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol; (-)-Oxedrine; oxedrine; (-)-Sympatol; (R)-4-(1-hydroxy-2-(methylamino)ethyl)phenol; 1-(4-Hydroxyphenyl)-2-methylaminoethanol; synephrin; ethaphene; analeptin; simpalon; (-)-Synephrine; Synephrine; MFCD00002370; D-synephrine; (-)-4-hydroxy-α-[(methylamino)methyl]benzenemethanol; sympathol; pentedrin; (-)-p-hydroxy-α-[(methylamino)methyl]benzyl alcohol
Molecular FormulaC9H13NO2
Molecular Weight167.21
Purity≥98.0 (HPLC)%
Density1.2±0.1 g/cm3
Boiling Point341.1±27.0 °C at 760 mmHg
Melting Point187 °C (dec.)(lit.)
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 94-07-5 |
| Catalog No. | 2A-9017836 |
| Chinese Name | 辛弗林 |
| Synonyms | synefrin; simpatol; EINECS 202-300-9; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol; (-)-Oxedrine; oxedrine; (-)-Sympatol; (R)-4-(1-hydroxy-2-(methylamino)ethyl)phenol; 1-(4-Hydroxyphenyl)-2-methylaminoethanol; synephrin; ethaphene; analeptin; simpalon; (-)-Synephrine; Synephrine; MFCD00002370; D-synephrine; (-)-4-hydroxy-α-[(methylamino)methyl]benzenemethanol; sympathol; pentedrin; (-)-p-hydroxy-α-[(methylamino)methyl]benzyl alcohol |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 341.1±27.0 °C at 760 mmHg |
| Melting Point | 187 °C (dec.)(lit.) |
| Appearance | powder |
| Storage Condition | This product should be kept sealed. |
| Application | Synephrine (Oxedrine) is a citrus-derived α-adrenergic and β-adrenergic agonist with sympathomimetic and structural similarities to ephedra and ephedrine alkaloids. |
| HTC | 2922199090 |
| MDL Number | MFCD00002370 |
| SMILES | N(CC(O)c1ccc(cc1)O)C |
| InChI | 1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3 |
| InChI Key | YRCWQPVGYLYSOX-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/17836_1_94_07_5.pdf |
| Bioactivity | Synephrine (Oxedrine) is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similarities to ephedra and ephedrine alkaloids[1][2]. Related Catalog Research Areas >> Endocrinology Target α-adrenergic and β-adrenergic[1] In Vivo Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine[2]. Animal Model: Portal vein ligation (PVL) or bile duct ligation (BDL) rats[2] Dosage: 1 mg/kg per 12 hours Administration: Oral gavage; for 8 days Result: The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced. References [1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90. [2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 341.1±27.0 °C at 760 mmHg Melting Point 187 °C (dec.)(lit.) Molecular Formula C9H13NO2 Molecular Weight 167.205 Flash Point 163.4±14.3 °C Exact Mass 167.094635 PSA 52.49000 LogP -0.03 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.572 InChIKey YRCWQPVGYLYSOX-UHFFFAOYSA-N SMILES CNCC(O)c1ccc(O)cc1 Storage condition 2-8°C |
| Use of | Synephrine (Oxedrine) is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similarities to ephedra and ephedrine alkaloids[1][2]. Properties Articles41 Name synephrine Synonym More Synonyms D-(-)-Synephrine Biological Activity Description Synephrine (Oxedrine) is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium, it has sympathomimetic and structural similarities to ephedra and ephedrine alkaloids[1][2]. Related Catalog Research Areas >> Endocrinology α-adrenergic and β-adrenergic[1] References [1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90. [2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8. Chemical & Physical Properties Molecular Formula C9H13NO2 Exact Mass 167.094635 PSA 52.49000 LogP -0.03 Index of Refraction 1.572 InChIKey YRCWQPVGYLYSOX-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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