CAS Number94-20-2
SynonymsChloropropamide; chlorpropamide; EINECS 202-314-5; 4-chloro-N-(propylaminocarbonyl)benzenesulfonamide; N-[(4-Chlorophenyl)sulfonyl]-N'-propylcarbamimidic acid; MFCD00079004; clorpropamida [INN_es]; 1-(4-chlorophenyl)sulfonyl-3-propylurea; 4-Chloro-N-(propylcarbamoyl)benzenesulfonamide
Molecular FormulaC10H13ClN2O3S
Molecular Weight276.74
Purity≥97%
Density1.4±0.1 g/cm3
Boiling Point433.5±47.0 °C at 760 mmHg
Melting Point128 °C
AppearanceWhite crystalline powder
EINECS202-314-5
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 94-20-2 |
| Catalog No. | 2A-9017842 |
| Chinese Name | 氯磺丙脲 |
| Synonyms | Chloropropamide; chlorpropamide; EINECS 202-314-5; 4-chloro-N-(propylaminocarbonyl)benzenesulfonamide; N-[(4-Chlorophenyl)sulfonyl]-N'-propylcarbamimidic acid; MFCD00079004; clorpropamida [INN_es]; 1-(4-chlorophenyl)sulfonyl-3-propylurea; 4-Chloro-N-(propylcarbamoyl)benzenesulfonamide |
| Molecular Formula | C10H13ClN2O3S |
| Molecular Weight | 276.74 |
| Purity | ≥97 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 433.5±47.0 °C at 760 mmHg |
| Melting Point | 128 °C |
| Appearance | White crystalline powder |
| Storage Condition | This product should be kept sealed. |
| Application | Chlorpropamide is an oral hypoglycemic agent used to treat non-insulin-dependent diabetes mellitus (NIDDM). |
| EINECS | 202-314-5 |
| HTC | 2935009090 |
| PubChem ID | 329774748 |
| MDL Number | MFCD00079004 |
| SMILES | CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 |
| InChI | 1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14) |
| InChI Key | RKWGIWYCVPQPMF-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/17842_1_94_20_2.pdf |
| Bioactivity | Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).Target:Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy. Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Na+/K+ ATPase Research Areas >> Endocrinology Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 433.5±47.0 °C at 760 mmHg Melting Point 128 °C Molecular Formula C10H13ClN2O3S Molecular Weight 276.740 Flash Point 216.0±29.3 °C Exact Mass 276.033539 PSA 83.65000 LogP 2.80 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.585 InChIKey RKWGIWYCVPQPMF-UHFFFAOYSA-N SMILES CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 Stability Stable. Combustible. |
| Use of | Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).Target:Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy. Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. Properties Articles47 Name chlorpropamide Synonym More Synonyms chlorpropamide Biological Activity Description Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).Target:Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy. Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Na+/K+ ATPase Research Areas >> Endocrinology Chemical & Physical Properties Exact Mass 276.033539 PSA 83.65000 Index of Refraction 1.585 InChIKey RKWGIWYCVPQPMF-UHFFFAOYSA-N Stability Stable. Combustible. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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